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Pharmacogenomics
Challenges and Opportunities in Therapeutic Implementation
A practical reference on pharmacogenomics that provides perspectives of the scientific and translational challenges and potential of molecular medicine
Yui-Wing Francis Lam (Edited by), Larisa H. Cavallari (Edited by)
9780123919182
Hardback, published 24 April 2013
510 pages, 125 illustrations
23.4 x 19 x 3 cm, 1.2 kg
"...a practical and indispensable resource on both the opportunities and challenges that allows readers to reflect on the future direction of pharmacogenomics while applying these observations to their own work or research."--Anticancer Research, February 2015 "Lam and Cavallari bring together pharmacy and other specialists from North America, Europe, and Asia for 13 chapters aimed at scientists, clinicians, and students in health and pharmaceutical sciences. The chapters consider the translation of pharmacogenomic findings into therapeutic applications from academic, regulatory, pharmaceutical, clinical, socioethical, and economic perspectives."--Reference and Research Book News, August 2013 "This book succeeds in providing a relevant and unique perspective, by international experts in the field, on the progress and challenges facing the translation of pharmacogenomics into clinical practice. I highly recommended it to anyone with an interest in the topic, from the essential basics to its role in the future practice of medicine."--Doody.com, August 2, 2013 "…this latest state-of-the-art book on pharmacogenomics successfully tackles the objectives described by its title. The key feature of the book is the in-depth discussion on a range of challenges currently facing pharmacogenomics in the widely publicised revolution in drug therapy… the Editors and the contributors are to be congratulated for their offering and this excellent book should serve well the needs of all those interested in the potential role of pharmacogenomic revolution in personalizing therapy…" – British Journal of Clinical Pharmacology, November 5, 2013
Approx.496 pages
SECTION 1 1 Principles of Pharmacogenomics: Pharmacokinetic, Pharmacodynamic, and Clinical Implications 2 Translating Pharmacogenomic Research to Therapeutic Potentials 3 Governmental and Academic Efforts to Advance the Field of Pharmacogenomics (PGRN CPIC, PharmGKB) Section 2 4a Pharmacogenomics in Cancer Therapeutics 4b A Look to the Future: Cancer epigenetics 5a Pharmacogenomics in Cardiovascular Diseases 5b A Look to the Future: Cardiovascular Pharmaco-epigenetics 6a Pharmacogenomics in Psychiatry Disorders 6b A Look to the Future: Epigenetics in psychiatric disorders and treatment 7 Role of Pharmacogenomics in Diabetes and Other Therapeutic Areas SECTION 3 8a Molecular Approaches, Models, and Techniques in Pharmacogenomic Research and Development 8b Molecular Approaches, Models, and Techniques in Pharmacogenomic Research and Development 9a Incorporating Pharmacogenomics in Drug Development Part 1: Rational study designs for pharmacogenetic research and therapy - A perspective from academia 9b Incorporating Pharmacogenomics in Drug Development Part 2: A perspective from industry 10 Ethnobridging and Pharmacogenomics SECTION 4 11 Beyond ELSIs - Where to from here? From 'Regulator' to Anticipating and Shaping the Innovation Trajectory in Personalized Medicine 12 The Economics of Pharmacogenomics SECTION 5 13 Integrating Genomics into Pharmacy Education and Practice: Pharmacogenomics is not enough
Subject Areas: Pharmacology [MMG]
