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Pharmaceutical Polymer Formulations and its Applications
Raj K. Keservani (Edited by), Keservani (Author), Eknath D. Ahire (Edited by), Rajesh Kumar Kesharwani (Edited by)
9781394172382, Wiley
Hardback, published 24 June 2025
512 pages
28 x 19 x 3 cm, 0.666 kg
The book is an essential resource for anyone in the pharmaceutical field, as it provides in-depth insights into the versatile roles of polymers in controlled drug delivery, highlighting their critical applications in product innovation, development, and manufacturing. Pharmaceutical Polymer Formulations and Its Applications provides an overview of the applications of pharmaceutical polymers in the vast field of controlled drug delivery. Polymers have the potential for a range of uses in the design of pharmaceutical dosage forms. They can be used as suspending, emulsifying, binding, or flocculant agents, as well as adhesives and packaging and coating materials. They can be used to make gels, nanoparticles, microparticles, and various capsules. Polymers have played an indispensable role in the manufacture of pharmaceutical products. This volume includes various polymers used in pharmacy based on their applications. The overviews focus on the use of pharmaceutical polymers for controlled drug delivery applications. Examples of pharmaceutical polymers and the principles of controlled drug delivery are outlined, and applications of polymers for controlled drug delivery are also discussed. Readers will find the book: Audience The book will interest chemists and healthcare professionals interested in pharmaceutical innovation using polymers.
Preface xxiii 1 Overview and Introduction of Polymers Used in Pharmaceuticals 1 1.1 Introduction 2 1.2 Classification of Polymers 2 1.3 Ideal Characteristics of Polymer 4 1.4 Characterization of Polymer 4 1.5 Applications of Polymers in Drug Delivery System 5 1.6 Conclusions 11 Acknowledgement 11 References 11 2 Biopolymers as Potential Carriers in the Novel Drug Delivery System 17 2.1 Introduction 18 2.2 Classification 18 2.3 Properties of Biopolymer 22 2.4 Characterization Techniques of Biopolymer 23 2.5 Frequently Studied Biopolymers 27 2.6 Future Prospective 33 2.7 Conclusion 33 Acknowledgements 34 References 34 3 Functional Polymers as Drug Carriers in Pharmaceuticals Development 41 3.1 Introduction 42 3.2 Polymers’ Role in Drug Delivery 45 3.3 Biomaterials for Delivery Systems 46 3.4 Polymers for Medication Delivery 46 3.5 How Polymers Release Drugs 49 3.6 Polymeric System Selection Criteria 50 3.7 Applications 58 3.8 Conclusion and Future Trends 63 Acknowledgements 64 References 64 4 Nanopolymer for Drug Delivery 71 4.1 Introduction 72 4.2 Classification of Polymer Nanoparticles 72 4.3 Polymers Used in the Manufacturing of PNPs 74 4.4 Conventionally Used Methods for Making Polymeric Nanoparticles (PNPS) 75 4.5 Pros and Cons of Polymeric Nanoparticles 80 4.6 Characterizing Polymeric Nanoparticles 81 4.7 Controlled Drug Delivery Polymeric Nanoparticles 84 4.8 Applications of Polymeric Nanoparticles 85 4.9 Recent Advances in the Field of PNPs 90 4.10 Future Prospects and Challenges 93 4.11 Conclusion 94 Acknowledgement 95 References 95 5 Natural Polymers for Drug Delivery 105 5.1 Introduction 106 5.2 General Methods of Extraction for Natural Polymers 108 5.3 Plant-Based Natural Polymers 111 5.4 Animal-Based Natural Polymers 119 5.5 Microorganism-Based Natural Polymers 123 5.6 Marine-Based Natural Polymers 127 5.7 Conclusion 131 Acknowledgement 131 References 131 6 Intelligent Drug Delivery Systems for Safe and Effective Cancer Treatment: Smart Bio-Responsive Polymers 143 6.1 Introduction 144 6.2 Smart Materials with Endogenous Triggering 147 6.3 Smart Materials with External Triggers 151 6.4 Biological Perspective 154 6.5 Conclusion and Future Perspective 164 Acknowledgment 165 References 165 7 Polymers and Their Uses in Drug Delivery 181 7.1 Introduction 182 7.2 A Polymeric Drug Delivery System’s Fundamentals 184 7.3 Classification of Polymers 184 7.4 Types of Polymers Used Depending Upon Their Inherent Property 186 7.5 Traditional Use of Polymers in Drug Delivery 192 7.6 Smart Polymers 192 7.7 Polymers in Novel Drug Delivery Systems 193 7.8 Recent Polymer Drug Delivery System Advances 194 7.9 Conclusion 194 Acknowledgement 195 References 195 8 Polymers in Oral Hygiene and Oral Drug Delivery 207 8.1 Introduction 208 8.2 Oral Hygiene 208 8.3 Polymers 209 8.4 History of Oral Polymeric Materials 210 8.5 Dental Polymers Natural and Synthetic 212 8.6 The Use of Polymers in Oral Hygiene 212 8.7 Polymers’ Part in the Oral Delivery of Drug 214 8.8 Oral Disease Management 217 8.9 Manufacturing of Dental Products 218 8.10 Polymers in Oral Health 218 8.11 Oral Drug Delivery System 226 8.12 Application of Polymers in Oral Dosage Forms 227 8.13 Conclusions 234 Acknowledgment 235 References 235 9 Polymers in Controlled Drug Delivery System 241 9.1 Introduction 241 9.2 Controlled Drug Delivery 244 9.3 Mechanism of Controlled Drug Delivery System 245 9.4 Polymers in Controlled Drug Delivery System 246 9.5 Conclusion 250 Acknowledgment 250 References 250 10 Polymers: An Update on Their Use in Ocular Drug Delivery Systems and Other Recent Developments 255 10.1 Introduction 256 10.2 Ideal Ophthalmic Drug Delivery System Characteristics 257 10.3 Routes of Administration of ODDS 257 10.4 Approaches for Ophthalmic Drug Delivery System 258 10.5 Polymers in the Delivery of Drug to the Eyes 263 10.6 Conclusion 267 Acknowledgement 267 References 267 11 Polymers and Approaches in Dental Preparations 273 11.1 Introduction 273 11.2 Polymers Used in Dentistry 276 11.3 Branches of Dentistry 279 11.4 Properties of Polymers 279 11.5 Applications of Polymers in Dentistry 281 11.6 Recent Advancements in Use of Polymers in Dentistry 284 11.7 Conclusion 286 Acknowledgment 286 References 286 12 Role and Types of Polymers Used in Cosmetics 291 12.1 Introduction 291 12.2 Classification of Cosmetics 292 12.4 Polymers in Cosmetics 296 12.5 Natural Polymers 297 12.7 Synthetic Polymers 302 12.8 Conclusion 304 Acknowledgement 304 References 305 13 Potential Natural Polymers in the Modern Drug Delivery Systems 309 13.1 Introduction 310 13.2 Type of Modern Drug Delivery System 311 13.3 Conclusion 326 Acknowledgments 326 References 326 14 Polymers in Nutritional Applications 333 14.1 Introduction 333 14.2 Classification 334 14.3 Advantages 336 14.4 Disadvantages 337 14.5 Application of Nutritional Polymer 338 14.6 Current Innovative Research in the Field of Nutritional Polymer 339 14.7 Future Perception to Nutritional Polymer Research 341 14.8 Conclusion 345 Acknowledgement 345 References 346 15 Green Polymers and Their Uses in Pharmacy 349 15.1 Introduction 350 15.2 Natural (Green) Polymer 352 15.3 Future Indications 359 15.4 Conclusion 360 References 361 16 Polymers in Gene Delivery 367 16.1 Introduction 368 16.2 Application of Polymers in Gene Delivery 370 16.3 Methods for Delivering Genes 370 16.4 Polymers Used 371 16.5 Future Prospective 379 16.6 Conclusion 379 References 380 17 Introduction, Overview and Various Uses of Synthetic Polymers in Pharmacy 385 17.1 Introduction 385 17.2 Synthetic Polymers in Pharmaceutical Formulation Developments 388 17.3 Synthetic Polymer-Conjugates Applications in Pharmaceuticals 393 17.4 Applications 395 17.5 Future Prospects 396 17.6 Conclusion 397 References 397 18 Semiconducting Polymer 405 18.1 Introduction 405 18.2 Polymers that are Conjugated as Semiconductors 408 18.3 Polymers with Semiconducting Properties 409 18.4 Applications of Semiconducting Polymers in Pharmaceutical and Medical Sciences Neural Applications 410 18.5 Conclusion 413 References 414 19 Nanostructured Polymer Systems and Pharmacy 421 19.1 Introduction 422 19.2 Nanostructured Polymers 424 19.3 Utilization of Polymeric Nanostructured Systems in the Drug Delivery System Nanocapsules 425 19.4 Future Perspective 432 19.5 Conclusion 433 References 434 20 Microstructured Polymer System and Its Application in Pharmacy 441 20.1 Introduction 442 20.2 Pharmaceutical Products Using Micro/Nanostructured Polymeric Materials 444 20.3 Polymeric Polymers as Pharmaceutical Drug Delivery Matrices 445 20.4 Methods for Preparing Nano- and Microparticles 453 20.5 Future Perspective 457 20.6 Conclusion 458 References 458 Index 467
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Subject Areas: Chemistry [PN]
