• Pediatric Liver Transplantation; A Clinical Guide (Hardback) 9780323636711
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Pediatric Liver Transplantation
A Clinical Guide

Detailed, in-depth coverage of this uniquely complex area of transplant medicine

Nedim Hadzic (Author), Ulrich Baumann (Author), Valérie MCLIN (Author)

9780323636711, Elsevier Health Sciences

Hardback, published 15 March 2021

512 pages, 100 illustrations (100 in full color)
27.6 x 21.5 x 3 cm, 1.22 kg

Written and edited by global leaders in the field, Pediatric Liver Transplantation: A Clinical Guide covers all aspects of treatment and management regarding this multifaceted procedure and unique patient population. This practical reference offers detailed, focused guidance in a highly templated, easy-to-consult format, covering everything from pre-transplantation preparation to surgical techniques to post-operative complications.

  • Provides an in-depth understanding of all aspects of pediatric liver transplantation, ideal for pediatric hepatologists, pediatric transplant surgeons, and others on the pediatric transplant team.
  • Covers all surgical techniques in detail, including split graft, living related, auxiliary, and domino.
  • Discusses pediatric liver transplantation consideration for an increasing number of additional metabolic, hematologic and renal conditions; breakthroughs in grafting and stem cell therapy; and techniques and present role of hepatocyte transplantation.
  • Uses a quick-reference templated format; each chapter includes an overview, pathophysiology, conventional management, controversies, and bulleted summary of key take-aways.
  • Includes state-of-the-art mini-reviews based on updated references and author experience throughout the text.
  • Features a full-color design with numerous algorithms, figures, and radiological and histopathological photos.
  • Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

  1. Evolution of transplantation medicine

    2. BRIEF HISTORY OF PLT

    HEALTH SYSTEM BACKGROUND REQUIREMENTS FOR PLT

  2. Before transplantation

    3. Brain death criteria

    Non-heart beating donors

    Donor procurement

    Managing a scarce resource: Differences in donor allocation across the world

    INDICATIONS AND CONTRAINDICATIONS (and their evolution) – General aspects

    (List of diagnoses)

    PREPARATION FOR PLT

    Medical (immunisations/cardiac/renal/neurological aspects)

    Surgical and Radiological aspects

    Psychological/Social aspects

  3. Paediatric liver transplantation

    4. ANAESTHETIC ASPECTS (Risk assessment)

    SURGICAL ASPECTS (Choice of donor for PLT, Prevention of thrombosis/anticoagulation)

    SURGICAL TECHNIQUES

    Split graft

    Living-related

    Auxiliary

    Domino

    Techniques and present role of hepatocyte transplantation

    STRATEGIES IN IMMUNE SUPPRESSION (Immune ablation, renal-sparing, steroid-sparing)

  4. Management after Transplantation

INTENSIVE CARE ASPECTS

ANTI-INFECTION STRATEGIES

Viral

Bacterial

Fungal

EARLY COMPLICATIONS

SURGICAL (biliary, vascular, etc.)

MEDICAL

ROLE OF HISTOLOGY AFTER PLT

ROLE OF RADIOLOGY AND INTERVENTIONAL RADIOLOGY AFTER PLT

LATE COMPLICATIONS

SURGICAL (graft re-modelling, secondary portal hypertension/shunts)

MEDICAL (recurrent disease post-PLT, de novo AIH, post-transplant lymphoproliferative disease, nephrotoxicity)

PSYCHOSOCIAL ASPECTS AFTER PLT

(social reintegration, medication adherence, family planning, education)

PROSPECTS FOR IMMUNE TOLERANCE (possibilities for safe withdrawal of immunosuppression)

TRANSITION TO ADULT SERVICES (smooth handover of care to a different system)

FUTURE REQUIREMENTS

Subject Areas: Paediatric medicine [MJW]
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