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Overcoming Drug Resistance in Gynecologic Cancers
Provides up-to-date information on the basic mechanisms of drug resistance, health disparities, commercial impacts and new strategies
Riyaz Basha (Volume editor), Sarfraz Ahmad (Volume editor)
9780128242995, Elsevier Science
Hardback, published 17 August 2021
388 pages, 70 illustrations (40 in full color)
23.5 x 19 x 2.6 cm, 0.95 kg
Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory and clinic. The book discusses topics such as lifestyle, nutrition and risk of gynecologic cancers, the financial impact of drug resistance, chemosensitizing agents and targeted therapies in cervical, endometrial and ovarian cancer, immunotherapy to overcome drug resistance, and genetic polymorphisms in gynecologic cancers. Additionally, it discusses ethnic and racial health disparity perspectives and future developments in chemosensitizing activities to reverse drug resistance in gynecologic cancers. It is a valuable resource for cancer researchers, oncologists, clinicians and other biomedical field members who are interested in new approaches to improve chemotherapy outcome in patients with gynecologic cancers.
1. Introduction to gynecologic cancers: An emphasis on pathogenesis, incidence sand diagnosis 2. Lifestyle, nutrition, and risk of gynecologic cancers 3. Drug Resistance in Gynecologic Cancers: Findings and Underlying Mechanisms 4. Mechanisms of Chemo-resistance and Approaches to Overcome its Impact in Gynecologic Cancers 5. Drug resistance in gynecologic cancers: Findings and underlying mechanismsCurrent Treatment Modalities in Major Gynecologic Cancers: Emphasis on Response Rates 6. Drug Resistance in Gynecologic Cancers: Emphasis on Non-coding RNAs and Drug Efflux Mechanisms 7. Genetic Polymorphisms in Gynecologic Cancers 8. Overcoming Drug Resistance in Cervical Cancer: Chemo-sensitizing Agents and Targeted Therapies 9. Immune Response, Inflammation Pathway Gene Polymorphisms and the Risk of Cervical Cancer 10. Overcoming Chemotherapy Resistance in Endometrial Cancer 11. Chemoresistance in Uterine Cancer: Mechanisms of Resistance and Current Therapies 12. Ovarian Cancer: Targeted Therapies and Mechanisms of Resistance 13. Overcoming Drug Resistance in Ovarian Cancer: Chemo-sensitizing Agents, Targeted Therapies 14. Resistance to Chemotherapy Among Ethnic and Racial Groups: Health Disparities Perspective in Gynecologic Cancers 15. Future Perspectives and New Directions in Chemosensitizing Activities to Reverse Drug Resistance in Gynecologic Cancers: Emphasis on Challenges and Opportunities
Subject Areas: Life sciences: general issues [PSA]
