Oral Delivery of Therapeutic Peptides and Proteins

Explores the industrial development, technological overview, and recent advances of oral delivery of peptides and proteins

Puneet Tyagi (Edited by), Anand Subramony (Edited by)

9780128210611, Elsevier Science

Paperback, published 22 August 2022

316 pages, 40 illustrations (15 in full color)
23.5 x 19 x 2.1 cm, 0.5 kg

Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport.

1. Formulation technologies being adopted for oral delivery of proteins and peptides
2. Modification of actives to make them more suited for oral delivery
3. Animal models and their shortcomings in assessing oral bioavailability
4. In vitro models to simulate drug absorption and transport
5. Futuristic technologies to improve oral bioavailability

Subject Areas: Biochemistry [PSB], Biophysics [PHVN], Pharmacology [MMG], Pharmaceutical industries [KNDP]