Optical Tweezers
Principles and Applications

A comprehensive guide to the theory, practice and applications of optical tweezers, combining state-of-the-art research with a strong pedagogic approach.

Philip H. Jones (Author), Onofrio M. Maragò (Author), Giovanni Volpe (Author)

9781107051164, Cambridge University Press

Hardback, published 3 December 2015

561 pages, 194 b/w illus. 18 tables
25.3 x 19.6 x 2.8 cm, 1.3 kg

'… until this book, there was no single reference source for the person interested in the theory and use of optical tweezers. In this book, the objects being trapped are generally microscale, although one chapter covers optical trapping of atoms … The supplementary website is well-organised and in addition to the software toolboxes, contains videos of tweezer construction, geometrical raytraces of various strapping geometries and an ongoing list of errata. In conclusion, it's about time a book like this has been issued, optical tweezers have been sufficiently incorporated in scientific research that students (and early stage researchers) need an introduction to the theory and practice on their use.' Andrew Resnick, Contemporary Physics

Combining state-of-the-art research with a strong pedagogic approach, this text provides a detailed and complete guide to the theory, practice and applications of optical tweezers. In-depth derivation of the theory of optical trapping and numerical modelling of optical forces are supported by a complete step-by-step design and construction guide for building optical tweezers, with detailed tutorials on collecting and analysing data. Also included are comprehensive reviews of optical tweezers research in fields ranging from cell biology to quantum physics. Featuring numerous exercises and problems throughout, this is an ideal self-contained learning package for advanced lecture and laboratory courses, and an invaluable guide to practitioners wanting to enter the field of optical manipulation. The text is supplemented by www.opticaltweezers.org, a forum for discussion and a source of additional material including free-to-download, customisable research-grade software (OTS) for calculation of optical forces, digital video microscopy, optical tweezers calibration and holographic optical tweezers.

1. Introduction
Part I. Theory: 2. Ray optics
3. Dipole approximation
4. Optical beams and focusing
5. Electromagnetic theory
6. Computational methods
7. Brownian motion
Part II. Practice: 8. Building an optical tweezers
9. Data acquisition and optical tweezers calibration
10. Photonic force microscope
11. Wavefront engineering and holographic optical tweezers
12. Advanced techniques
Part III. Applications: 13. Single molecule biophysics
14. Cell biology
15. Spectroscopy
16. Optofluidics and lab on a chip
17. Colloid science
18. Microchemistry
19. Aerosol science
20. Statistical physics
21. Nanothermodynamics
22. Plasmonics
23. Nanostructures
24. Laser cooling and trapping of atoms
25. Towards the quantum regime at the mesoscale
Index.

Subject Areas: Chemical engineering [TDCB], Biophysics [PHVN], Optical physics [PHJ], Biomedical engineering [MQW]