Nucleic Acid Nanotheranostics
Biomedical Applications

Explores improvements and new trends in the fabrication of nanostructures as theranostic multifunctional carriers in gene therapy

Marco Filice (Edited by), Jesús Ruiz-Cabello (Edited by)

9780128144701

Paperback / softback, published 28 February 2019

491 pages
23.4 x 19 x 3.1 cm, 0.45 kg

Nucleic Acid Nanotheranostics: Biomedical Applications offers a comprehensive overview of improvements and new trends in fabrication of nanostructures as theranostic multifunctional carriers in gene therapy. With a strong focus on medical applications (comprising diagnosis, therapy and imaging), the book also examines gene therapy in an individual patient’s cells or tissues to treat genetic diseases. Sections cover Biomedical and Diagnostic applications of Nucleic Acids, Biologic and Synthetic Advanced Nanostructures for nucleic acid delivery, and important considerations of nanomedicine. This book is a valuable guide for materials scientists, physicians, chemists and engineers, but is also ideal for clinicians wishing to expand their knowledge.

1. Therapeutic oligonucleotides against cancer: Recent approaches and new perspectives 2. Small interfering RNA-mediated silencing of ribophorin II (RPN2) gene: The way forward for the treatment of malignant breast cancer 3. Non-coding RNAs in cardiovascular disease 4 MicroRNAs in respiratory diseases 5. State of the art and future direction for the analysis of cell-free circulating DNA 6. Aptamer-based strategies for diagnosis 7. Viral Vectors for Treatment of Human Disease: Therapeutic and Manufacturing Challenges 8. Nonviral nucleic acid therapy: Peptiplexes 9. Controlling Protein Expression by Delivery of RNA Therapeutics Using Lipid Nanoparticles 10. Advanced Polymers for Nonviral Gene Delivery 11. Nonviral Gene Therapy: Design and Application of Inorganic Nanoplexes 12. Extracellular vesicles as a novel nanocarriers for therapeutic delivery 13. Nanocarrier-based Gene therapy Imaging Strategies 14. The state-of-art of investigational and approved nanomedicine products for nucleic acid delivery

Subject Areas: Materials science [TGM], Biotechnology [TCB], Biochemistry [PSB], Biomedical engineering [MQW]