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Non-Natural Amino Acids
This volume aims to provide fundamental insights into how proteins work within the context of complex biological systems of biomedical interest
Tom W. Muir (Volume editor), John N. Abelson (Volume editor)
9780123743107, Elsevier Science
Hardback, published 22 September 2009
350 pages
22.9 x 15.1 x 2.5 cm, 0.63 kg
By combining the tools of organic chemistry with those of physical biochemistry and cell biology, Non-Natural Amino Acids aims to provide fundamental insights into how proteins work within the context of complex biological systems of biomedical interest. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. With more than 400 volumes published, each Methods in Enzymology volume presents material that is relevant in today's labs -- truly an essential publication for researchers in all fields of life sciences.
(Tentative)
1. Protein Engineering with the Traceless Staudinger Ligation (Ronald T. Raines and Annie Tam)
2. Mechanistic studies of RNR using unnatural amino acids and semisynthesis (Joann Stubbe)
3. Using Expressed Protein Ligation to Probe the Substrate Specificity of Lantibiotic Synthetases (Wilfred van der Donk and Xingang Zhang)
4. Protein Phosphorylation by Semisynthesis: From Paper to Practice (Phlip A. Cole,Lawrence M. Szewczuk, and Mary Katherine Tarrant)
5. Mechanistic studies of semisynthetic ion channels (Francis Valiyaveetil)
6. Semi-synthesis of proteins using split inteins (Henning D. Mootz, Christina Ludwig, Joachim Zettler, Daniel Garbe)
7. Segmental Isotopic Labeling of Proteins for Nuclear Magnetic Resonance (David Cowburn, Dongsheng Liu, Rong Xu)
8. Use of intein-mediated protein ligation strategies for the fabrication of functional protein arrays (Shao Q Yao, Souvik Chattopadhaya, Farhana B. Abu Bakar)
9. Expressed Protein Ligation for Metalloprotein Design and Engineering (Yi Lu, Wilfred van der Donk, Kenneth Clark)
Subject Areas: Cellular biology [cytology PSF], Proteins [PSBC], Biochemistry [PSB]
