Non-Canonical Autophagy
Mechanisms and Pathophysiological Implications

Offers a valuable, in-depth guide to the mechanistic and pathophysiological features of non-canonical autophagy

Giulia Petroni (Edited by), Lorenzo Galluzzi (Edited by)

9780128205389, Elsevier Science

Paperback, published 26 April 2021

182 pages, 75 illustrations (25 in full color)
22.9 x 15.1 x 1.3 cm, 0.29 kg

"This is an excellent book covering molecular mechanisms underlying non-canonical autophagy and the therapeutic potential and development of autophagy modulators. There are very few books which cover the molecular mechanisms underlying non-canonical autophagy. Weighted Numerical Score: 85 - 3 Stars" --© Doody’s Review Service, 2021, Omer Iqbal, reviewer, expert opinion

Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between ‘canonical’ and ‘non-canonical’ forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of ‘non-canonical’ autophagy. The book discusses all forms of ‘non-canonical’ autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying ‘non-canonical’ autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and effective treatment strategies.

1. Introduction: canonical vs non-canonical autophagy 2. Overview of Canonical Autophagy  3. Overview of Non-Canonical Autophagy 4. LC3-associated phagocytosis (LAP) 5. Autophagy-dependent cell death (ADCD)  6. Therapeutic targeting of non-conventional autophagy: potential benefits and pitfalls  

Subject Areas: Cellular biology [cytology PSF], Molecular biology [PSD]