Neurotoxicity of Drugs of Abuse

Are the adverse effects of some drugs of abuse on the nervous system reversable; not necessarily

Lucio G. Costa (Volume editor), Michael Aschner (Volume editor), William Slikker Jr. (Volume editor)

9780323915854, Elsevier Science

Hardback, published 15 September 2022

194 pages
22.9 x 15.2 x 1.9 cm, 0.45 kg

Neurotoxicity of Drugs of Abuse, Volume Eight provides carefully crafted reviews on the disruptive impact of drugs of abuse on the central nervous system. The neurotoxicity potential of several agents including marijuana, fentanyl, and ketamine are carefully reviewed, and their short-term and chronic effects are categorized. Pharmacokinetic profiles as well as mechanisms of action for these and other drugs of abuse such as alcohol and nicotine are also evaluated. The implications of short and long-term abuse for agents such as PCP are also characterized. The reader will come away with a fuller understanding of the adverse effects of drugs of abuse on the nervous system.

Preface William Slikker, Jr. 1. Cannabinoids G. Jean Harry 2. Converging mechanisms in ethanol neurotoxicity Miriam Beatriz Virgolini and Ricardo Marcos Pautassi 3. Neurotoxicology of nicotine and tobacco Edward D. Levin 4. The neurotoxic potential of opioids including fentanyl and fentanyl analogs R. Daniel Mellon 5. Phencyclidine (PCP)-induced neurotoxicity and behavioral deficits Cheng Wang, Shuliang Liu, Leah E. Latham, Fang Liu, Tucker A. Patterson and William Slikker Jr 6. The mysterious beauty of ketamine: benefits and risks Donald R. Mattison, Abdallah Alami, Thomas J. Moore and G. Caleb Alexander

Subject Areas: Toxicology [non-medical PSBT], Neurosciences [PSAN]