Neurobiology of Psychiatric Disorders

A comprehensive and integrated review of psychiatric care and its scientific foundations

Thomas E Schlaepfer (Edited by), Charles B. Nemeroff (Edited by)

9780444520029, Elsevier Science

Hardback, published 26 June 2012

762 pages, Illustrated
26 x 18.3 x 3.9 cm, 2.35 kg

This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment.

1. Psychiatry and neuroscience history
2. Receptor signaling and the cell biology of synaptic transmission
3. Human genetics of schizophrenia
4. Neurological and psychiatric aspects of emotion
5. Research methods: cognitive neuropsychological methods
6. Structural imaging in psychiatric disorders
7. Human functional neuroimaging
8. Neurotransmitters and neuropeptides in depression
9. Animal models of psychiatric disorders
10. Psychiatric epidemiology
11. Emerging methods in the molecular biology of neuropsychiatric disorders
12. Clinical psychoneuroimmunology
13. Psychiatric rating scales
14. Unipolar depression
15. Bipolar disorder
16. The neurobiology and treatment of late-life depression
17. Seasonal affective disorder
18. Biological and clinical framework for post-traumatic stress disorder
19. Generalised anxiety disorder
20. Panic disorder
21. Obsessive compulsive disorder
22. Attention deficit hyperactivity disorder
23. Autism and related disorders
24. Substance abuse disorders
25. Cognitive impairment in schizophrenia: profile, course and neurobiological determinants
26. Eating disorders: anorexia and bulimia nervosa
27. Personality disorders
28. Psychiatric, non motor aspects of Parkinson’s disease
29. Stroke
30. Huntingdon’s disease
31. Sleep disorders
32. Depression and cardiovascular disorders
33. Psychiatric disorders among cancer patients
34. Chronic fatigue syndrome
35. Neurocognitive deficits in patients with human immunodeficiency virus infection
36. Gastrointestinal disorders
37. Role of psychotherapy in the management of psychiatric diseases
38. Pharmacology and neuroimaging of antidepressant action
39. Antipsychotic drugs
40. Anxiolytics
41. Brain stimulation therapies for neuropsychiatric disease
42. Chronotherapeutics, light and wake therapy as a class of interventions for affective disorders
43. Pharmacogenetics of antidepressants and mood stabilisers

Subject Areas: Neurosciences [PSAN], Neurology & clinical neurophysiology [MJN], Abnormal psychology [JMP]