Neurobiology of Peripheral Nerve Regeneration

Summary of what peripheral nerves are, how they can be damaged, and the sequence of events involved in their regeneration.

Douglas W. Zochodne (Author)

9780521867177, Cambridge University Press

Hardback, published 23 October 2008

284 pages, 31 b/w illus. 32 colour illus.
25.3 x 18 x 1.9 cm, 0.78 kg

Peripheral nerve disorders are among the most common neurological problems that clinicians face, yet few therapies and interventions are available to arrest or reverse the damage associated with them. Summarising this important, but neglected, area of neuroscience, Doug Zochodne addresses the peripheral nervous system and its unique neurobiology. He summarises current basic ideas about the molecular mechanisms involved in both nerve degeneration and regeneration and what approaches can be used to address it experimentally. Heavily illustrated throughout, and including a 32 page colour plate section, this book will serve as a valuable reference for academic researchers and graduate students.

1. Introduction
2. The intact peripheral nerve tree
3. Injuries to peripheral nerves
4. Addressing nerve regeneration
5. Early regenerative events
6. Consolidation and maturation of regeneration
7. Regeneration and the vasa nervorum
8. Delayed reinnervation
9. Trophic factors and peripheral nerves
10. The nerve microenvironment.

Subject Areas: Neurosciences [PSAN], Neurology & clinical neurophysiology [MJN]