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Neurobiology of Brain Disorders
Biological Basis of Neurological and Psychiatric Disorders
Offers comprehensive coverage on the neurobiology of brain disorders
Michael J. Zigmond (Edited by), Clayton A. Wiley (Edited by), Marie-Françoise Chesselet (Edited by)
9780323856546, Elsevier Science
Hardback, published 19 May 2022
1134 pages
27.6 x 21.6 x 5.2 cm, 3.22 kg
Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders, Second Edition provides basic scientists a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases. Topics include developmental, autoimmune, central, and peripheral neurodegeneration, infectious diseases, and diseases of higher function. Organized by individual disorder, each chapter includes coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. This volume reflects progress in the field since publication of the first edition, with fully updated chapters, and new chapters on isolation, aging, global diseases, vascular diseases, and toxic/metabolic disease. New disorder coverage includes fibromyalgia, chronic fatigue, Restless Legs Syndrome, myasthenia gravis, and more.
Section I: Introductions 1. A Clinical Neuroscientist’s Overview of Disorders of the Brain 2. Disease around the world Section II. Developmental Disorders 3. Introduction 4. Developmental Disabilities and Metabolic Disorders 5. Attention Deficit/Hyperactivity Disorder 6. Down Syndrome: A Model for Chromosome Abnormalities 7. Autism Spectrum Disorder 8. Rett Syndrome: From the Involved Gene(s) to Treatment 9. Fragile X-Associated Disorders Section III. Diseases of The Peripheral Nervous System 10. Introduction 11. Myasthenia Gravis 12. Muscular Dystrophy 13. Peripheral Neuropathies 14. Diabetes and Cognitive Dysfunction, Catrina Sims-Robinson Section IV. Diseases of the Central Nervous System and Neurodegeneration 15. Introduction 16. Spinal Cord Injury 17. Vascular Diseases of the Nervous System 18. Toxic/Metabolic Diseases of the Nervous System 19. Traumatic Brain Injury 19. Epilepsy 20. Amyotrophic Lateral Sclerosis 21. Parkinson Disease and Other Synucleinopathies 22. Huntington Disease 23. Alzheimer Disease 24. Cerebrovascular Disease – Stroke 25. Prion Diseases Section V. Infectious and Immune-Mediated Diseases Affecting the Nervous System 26. Introduction 27. Role of Inflammation in Neurodegenerative Diseases 28. Role of Inflammation in Psychiatric Disease 29. Infections and Nervous System Dysfunction 30. Pathobiology of CNS Human Immunodeficiency Virus Infection 31. Emergent Viral infections of the Nervous System 32. Autoimmune and Paraneoplastic Neurological Disorders 33. Fibromyalgia and Chronic Fatigue 34. Multiple Sclerosis Section VI. Diseases of Higher Function 35. Introduction 36. Disorders of Higher Cortical Function 37. Disorders of Frontal Lobe Function 38. Stress 39. Addictions 40. Sleep Disorders 41. Restless Legs Syndrome 42. Fear-Related Anxiety Disorders and Post-Traumatic Stress Disorder 43. Obsessive–Compulsive Disorder 44. Schizophrenia 45. Bipolar Disorder 46. Pain: From Neurobiology to Disease 47. Migraine 48. Depression and Suicide Section VII. Diseases of the Nervous System and Society 49. Introduction 50. The Neurological and Psychiatric Consequence of Aging 51. Advances in Ethics for the Neuroscience Agenda 52. Burden of Neurological Disease 53. Stress, Health, and Disparities 54. The impact of isolation on brain health
Subject Areas: Neurosciences [PSAN], Psychiatry [MMH], Neurology & clinical neurophysiology [MJN]
