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Navigating Non-coding RNA
From Biogenesis to Therapeutic Application
Offers a detailed overview of the field of non-coding RNA from basic biology to clinical application
Joanna Sztuba-Solinska (Edited by)
9780323904063, Elsevier Science
Paperback / softback, published 22 June 2023
448 pages, 60 illustrations (30 in full color)
22.9 x 15.2 x 2.5 cm, 0.45 kg
Navigating Non-coding RNA: From Biogenesis to Therapeutic Application provides a concise overview of the field of non-coding RNA (ncRNA). Chapters cover the history of discoveries that have occurred in the area of ncRNA, specific types of ncRNA, housekeeping ncRNAs such as ribosomal RNA, transfer RNA, small nuclear RNA and telomerase RNA, regulatory ncRNAs such as microRNA, small interfering RNA, long non-coding RNA and Y RNA. Biogenesis, structure, function, and regulation of each of these are also explored in addition to traditional and cutting-edge methods for the identification, functional characterization and structural characterization of ncRNA. The book also focuses on the different types of epitranscriptomic modifications and their involvement in regulating ncRNA structure, stability and intermolecular interactions in addition to the role of ncRNAs in a range of diseases and potential therapeutic applications.
1. Non-coding RNAs: history and definition
2. Housekeeping ncRNAs
3. Regulatory ncRNAs
4. Non-coding RNAs: mechanisms of action
5. Identification of non-coding RNAs
6. Functional characterization of non-coding RNAs
7. Structural characterization of non-coding RNAs
8. Regulation of Non-coding RNAs
9. Non-coding RNAs in human non-infectious diseases
10. Non-coding RNAs in human infectious diseases
Subject Areas: Molecular biology [PSD]
