Natural Product Biosynthesis by Microorganisms and Plants Part B

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field, covering natural product biosynthesis by microorganisms and plants

David A. Hopwood (Volume editor)

9780123942913, Elsevier Science

Hardback, published 3 December 2012

462 pages
22.9 x 15.1 x 2.9 cm, 0.75 kg

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The second of 3 volumes covering Natural product biosynthesis by microorganisms and plants.

1. In vivo production of thiopeptide variants
2. Microviridin biosynthesis
3. Cyclotide isolation and characterization
4. Ribosomally-encoded cyclic peptide toxins from mushrooms
5. The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: novel function for a non-ribosomal peptide synthetase
6. Discovery and biosynthesis of phosphonate and phosphinate natural products
7. RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins
8. Fe(II)-dependent, uridine-5’-monophosphate a-ketoglutarate dioxygenases in the synthesis of 5’-modified nucleosides
9. Heme-dependent Tailoring Enzymes in Natural Product Biosynthesis: Spectroscopic Characterisation of the L-tryptophan-nitrating Cytochrome P450 TxtE
10. Oxidative Tailoring Reactions Catalysed by Non-heme Iron-dependent Enzymes: Streptorubin B Biosynthesis as an Example
11. The rare fluorinated natural products and biotechnological prospects for fluorine enzymology
12. Enzymatic chlorination and bromination
13. Prenyltransferases of the dimethylallyltryptophan synthase superfamily
14. Serine carboxypeptidase-like acyltransferases from plants
15. 4-Methylideneimidazole-5-one-containing aminomutases in enediyne biosynthesis
16. Tailoring enzymes acting on carrier protein-tethered substrates in natural product biosynthesis
17. High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer
    

Subject Areas: Microbiology [non-medical PSG], Enzymology [PSBZ], Biochemistry [PSB]