Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology

Discusses how the use of nanotechnology in biomaterials processing can help create cheaper, more effective pharmaceutical products

Alexandru Mihai Grumezescu (Edited by)

9780128136294

Paperback, published 29 November 2017

696 pages
23.4 x 19 x 4.2 cm, 1.43 kg

Approx.676 pages

1. Fabrication of polymeric core-shell nanostructures 2. Emulsification-diffusion method to obtain polymeric nanoparticles: two decades of research 3. Tools and Techniques for the optimized synthesis, reproducibility and scale up of desired nanostructures from plant derived material and their role in pharmaceutical properties 4. Scale up of biopharmaceuticals production 5. Physicochemical and morphological characterization of pharmaceutical nanocarriers and mathematical modelling of drug encapsulation/release mass transfer processes 6. Biopharmaceutics and pharmacokinetics of multifunctional nanoparticles 7. Technological delivery systems to improve biopharmaceutical properties 8. From physicochemically stable nanocarriers to targeted drug delivery: in-vivo pharmacokinetic, pharmacodynamic and biodistribution studies 9. Sterile dosage forms loaded nanosystems for parenteral, nasal, pulmonary and ocular administration 10. Quantitative Characterization of Targeted Nanoparticulate Formulations for Prediction of Clinical Efficacy 11. Analytical tools for reliable in vitro and in vivo performance testing of drug nanocrystals 12. Application of one-step affinity purification of drug-binding proteins with practical magnetic nanoparticles to drug discovery 13. Molecularly Imprinted Polymers as Separation Tools 14. Detection of DNA damage induced by nanomaterials 15. Pharmacological usage of an enzyme inhibitor – a selective inhibitor of 3-mercaptopyruvate sulfurtransferase reaction intermediate to control generation of polysulfide 16. Regulatory Consideration in Nanotechnology Based Drug Products

Subject Areas: Electronics & communications engineering [TJ], Biomedical engineering [MQW], Pharmacology [MMG]