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Nanomaterials in Tissue Engineering
Fabrication and Applications
A K Gaharwar (Edited by), S Sant (Edited by), M J Hancock (Edited by), S A Hacking (Edited by)
9780857095961, Elsevier Science
Hardback, published 31 July 2013
468 pages
23.3 x 15.6 x 2.9 cm, 0.87 kg
"...a timely contribution for researchers working at the intersection of the highly active fields of nanomaterials and tissue engineering...non-experts who want to jump right will likely find much of the material accessible..." --Biomat.net, October 2013 "The book…captures the convergence of cutting-edge research at the interface of nanobiomaterials, and tissue engineering. the book provides a comprehensive introduction and overview of the latest developments in nanomaterials for tissue engineering for anyone new to the subjects, and is a useful reference for advanced professionals." --MaterialsViews.com, March 4, 2014 "…this volume addresses a previously underserved niche within the spectrum of biomaterials/tissue engineering research [and] remains firmly focused on the challenges and opportunities of nanomaterials applied in tissue engineering." --James Henderson The Biomaterials Network
Nanomaterial technologies can be used to fabricate high-performance biomaterials with tailored physical, chemical, and biological properties. They are therefore an area of interest for emerging biomedical technologies such as scaffolding, tissue regeneration, and controlled drug delivery. Nanomaterials in tissue engineering explores the fabrication of a variety of nanomaterials and the use of these materials across a range of tissue engineering applications.
Part one focuses on the fabrication of nanomaterials for tissue engineering applications and includes chapters on engineering nanoporous biomaterials, layer-by-layer self-assembly techniques for nanostructured devices, and the synthesis of carbon based nanomaterials. Part two goes on to highlight the application of nanomaterials in soft tissue engineering and includes chapters on cardiac, neural, and cartilage tissue engineering. Finally, the use of nanomaterials in hard tissue engineering applications, including bone, dental and craniofacial tissue engineering is discussed in part three.
Nanomaterials in tissue engineering is a standard reference for researchers and tissue engineers with an interest in nanomaterials, laboratories investigating biomaterials, and academics interested in materials science, chemical engineering, biomedical engineering and biological sciences.
Contributor contact details Woodhead Publishing Series in Biomaterials Foreword Introduction Chapter 1: Biomedical nanomaterials in tissue engineering Abstract: 1.1 Introduction 1.2 Overview of nanomaterials in tissue engineering 1.3 Biomedical nanomaterials in tissue engineering applications 1.4 Future trends Part I: Fabrication of nanomaterials for tissue engineering applications Chapter 2: Synthesis of polymeric nanomaterials for biomedical applications Abstract: 2.1 Introduction 2.2 Types of polymers used in nanomaterials 2.3 Synthesis of polymeric nanoparticles 2.4 Synthesis of polymeric scaffolds 2.5 Characterization of the nanomaterials 2.6 Future trends Chapter 3: Engineering nanoporous biomaterials Abstract 3.1 Introduction 3.2 Nanotubes and etched nanoporous surfaces 3.3 Self-assembled supramolecular organic templates 3.4 Self-assembled colloidal templates 3.5 Conclusion Chapter 4: Layer-by-layer self-assembly techniques for nanostructured devices in tissue engineering Abstract: 4.1 Introduction 4.2 Interaction between biomaterials as ingredients for multilayer formulations 4.3 Scalability to three dimensions 4.4 Application of nanostructured multilayer devices in tissue engineering Conclusion Chapter 5: Synthesis of carbon based nanomaterials for tissue engineering applications Abstract: 5.1 Introduction 5.2 Carbon nanotubes and fibers 5.3 Fullerenes (C60) 5.4 Graphene 5.5 Nanodiamond systems 5.6 Carbon-nanostructured materials 5.7 Conclusion Chapter 6: Fabrication of nanofibrous scaffolds for tissue engineering applications Abstract: 6.1 Introduction 6.2 Methods for nanofibrous scaffolds fabrication 6.3 Surface modification of nanofibrous scaffolds 6.4 Applications of nanofibrous scaffolds in tissue engineering 6.5 Conclusion Chapter 7: Fabrication of nanomaterials for growth factor delivery in tissue engineering Abstract: 7.1 Introduction 7.2 Strategies for controlled growth factor delivery in tissue engineering 7.3 Nanostructures for growth factor delivery in tissue engineering 7.4 Nanofibers 7.5 Nanoparticles 7.6 Strategies for dual growth factor, drug and gene delivery 7.7 Clinical prospective of nanostructures with growth factor delivery in tissue engineering 7.8 Conclusion and future trends Part II: Application of nanomaterials in soft tissue engineering Chapter 8: Nanomaterials for engineering vascularized tissues Abstract: 8.1 Introduction 8.2 Biocomplexity of vascularized tissues 8.3 Engineering nanomaterials to improve vascularization of tissues 8.4 Clinical progress 8.5 Conclusion and future trends Chapter 9: Nanomaterials for cardiac tissue engineering Abstract: 9.1 Introduction 9.2 Heart muscle structure and diseases 9.3 Cardiac tissue engineering (CTE) 9.4 Application of nanomaterials and nanofabrication methods in CTE 9.5 Case study: magneto-mechanical cell stimulation to promote CTE 9.6 Conclusion and future trends 9.7 Acknowledgements Chapter 10: Nanomaterials for neural tissue engineering Abstract: 10.1 Introduction to neural tissue engineering 10.2 Nano-scaffold design techniques 10.3 Nano-structures 10.4 Biomaterials for scaffold design 10.5 Drawbacks of the use of nanomaterials 10.6 Conclusion and future trends 10.7 Acknowledgements Chapter 11: Nanomaterials for cartilage tissue engineering Abstract: 11.1 Introduction 11.2 Cartilage biology and structure 11.3 Clinical approaches in the treatment of cartilage defects 11.4 Nanomaterials: strategies for cartilage regeneration 11.5 Conclusion Chapter 12: Biomaterials and nano-scale features for ligament regeneration Abstract: 12.1 Introduction 12.2 Anterior cruciate ligament (ACL) composition, structure and properties 12.3 Injury, healing and treatment of the ACL 12.4 Engineered scaffold materials for ligament regeneration 12.5 Methods for enhancing engineered scaffolds for ligament regeneration 12.6 Conclusion and future trends Part III: Application of nanomaterials in hard tissue engineering Chapter 13: Nanomaterials for hard–soft tissue interfaces Abstract: 13.1 Introduction 13.2 Nanoparticles 13.3 Nanofibers 13. 4 Strategies incorporating nanomaterials in hard–soft tissue interfaces 13 5 Conclusion and future trends Chapter 14: Mineralization of nanomaterials for bone tissue engineering Abstract: 14.1 Bone: a nanobiocomposite material 14.2 Collagen as a biomaterial 14.3 Approaches to the mineralization of collagenous constructs 14.4 Conclusion Chapter 15: Nanomaterials for dental and craniofacial tissue engineering Abstract: 15.1 Introduction 15.2 Nanotechnology for engineered substrates 15.3 Engineering mineralized collagenous craniofacial structures 15.4 Nano-scale scaffolds with integrated delivery systems 15.5 Micro/nano-arrays as libraries for high-throughput characterization 15.6 Conclusion Index
Subject Areas: Materials science [TGM]
