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Nanoengineered Materials for Medical and Healthcare Applications
Radhakrishnan Edayileveettil Krishnankutty (Edited by), R E.K. (Author), Ashitha Jose (Edited by), Visakh P. M. (Edited by)
9781119791645, Wiley
Hardback, published 28 May 2025
384 pages
25 x 15 x 1.5 cm, 0.666 kg
This book is a comprehensive guide on the new-generation nanoengineered materials’ contribution to the ongoing development of medical devices and other healthcare applications. Nanotechnology has revolutionized cutting-edge medical approaches, including gene therapy, targeted drug delivery, treatment of various chronic and genetic diseases, cancer diagnosis and treatment modalities, and more, leading to the establishment of personalized treatment regimens. The book reports on various nanoparticles, such as metallic and non-metallic nanoparticles, nano-micelles, liposomal nanoparticles, and polymer nanoparticles, being utilized in various aspects of medical and healthcare applications. In addition, novel natural product-based nanomaterials and nanomaterial complexes are also detailed, showing their potential applications. The impact of nanotechnology in promoting bone regeneration and serving as novel dental implants is investigated, along with its applications in skincare. The book examines the crucial role nanotechnology plays in the development of various antimicrobial materials and surfaces, which are being used in the medical sector, including numerous types of wound healing materials, antimicrobial textiles, and PPEs, as well as face masks and gloves. The book concludes with a chapter on nano-coated medical devices. Audience The audience comprises researchers, engineers, and scientists in materials science, nanotechnology, and bioengineering working in the biomedical and bioscience areas and industries.
Preface xv 1 Nanomedicine—History and Recent Trends 1 List of Abbreviations 1 1.1 Introduction 2 1.2 Definition 3 1.3 History 4 1.4 The Main Aim and Recent Trends 7 1.5 Challenges 16 1.6 Current Status and Future Perspectives 18 1.7 Conclusion 19 References 19 2 Nanoparticles and Micelles as Biomedicine 25 2.1 Nanoparticles 26 2.2 Nanoparticles as Biomedicine 29 2.3 Micelles as Biomedicine 33 2.4 Conclusion 45 References 45 3 Natural Product-Based Nanomedicine 53 List of Abbreviations 54 3.1 Introduction 54 3.2 Natural Product 55 3.3 Natural Product-Based Nanomedicine 62 3.4 Conclusion 80 References 80 4 Engineered Liposomal Nanoparticles and Their Medical Applications 93 4.1 Introduction 94 4.2 Liposome Nanoparticles and Their Different Types 94 4.3 Ethosomes (Ethanolic Liposomes) 105 4.4 Types of Engineered Liposomal Drug Delivery Platforms 109 4.5 Medical Applications of Engineered Liposomes 113 4.6 Challenges and Limitations 119 4.7 Conclusions 119 Acknowledgment 126 References 126 5 Development and Characterization of Polymer Nanocomposites for Clinical Applications 137 Abbreviations 137 5.1 Introduction 138 5.2 Polymer Nanocomposites 140 5.3 Synthesis of Polymer Nanocomposites 145 5.4 Characterization Techniques 148 5.5 Clinical Applications of Polymer Nanocomposites 149 5.6 Polymer Nanocomposites for Clinical Application 151 5.7 Conclusion 158 5.8 Future Perspective 158 Acknowledgement 158 References 159 6 Bionanocomposites for Clinical Applications 167 6.1 Introduction 167 6.2 Raw Materials Used for Bionanocomposites Preparation 168 6.3 Bionanocomposite Application in the Clinical Field 172 Conclusion 189 References 190 7 Nanomodified Polymers for Bone Regeneration and as Dental Implant 199 List of Abbreviations 200 7.1 Introduction 201 7.2 Nanomodified Polymers 205 7.3 Nanomodified Polymers for Bone Regeneration 206 7.4 Nanomodified Polymers for Dental Implants 217 7.5 Conclusion 218 References 219 8 Stimuli-Responsive Nanoengineered Scaffolds in Medicine and Healthcare 227 Abbreviations 227 8.1 Introduction 228 8.2 pH-Responsive Nanoengineered Scaffolds 229 8.3 Light-Responsive Nanoengineered Scaffolds 230 8.4 Redox-Responsive Nanoengineered Scaffolds 231 8.5 Magnetic-Responsive Nanoengineered Scaffolds 232 8.6 Electro-Responsive Nanoengineered Scaffolds 232 8.7 Limitations and Challenges 233 8.8 Conclusion 234 References 234 9 Skin Care Applications of Nanomaterials 237 9.1 Introduction 237 9.2 The Use of Nanomaterials in Skin Care 239 9.3 Different Types of Nanomaterials Used in Cosmetics 241 9.4 Frequently Used Nanotechnology-Based Cosmetic Products 247 9.5 Future Goal 253 9.6 Conclusion 254 References 254 10 Nanocoated Wound Healing Materials 261 10.1 Introduction 261 10.2 Physiology of Wound Healing 264 10.3 Significance of Nanoparticles in Wound Healing 267 10.4 Nanoparticles Used for Wound Healing 268 10.5 Limitations 280 10.6 Future Perspectives 280 10.7 Conclusion 280 Acknowledgment 281 References 281 11 Nanomaterial Based Medical Textiles for Antimicrobial Applications 295 List of Abbreviations 295 11.1 Introduction: Medical Textiles 296 11.2 Microorganisms 296 11.3 Antimicrobials 297 11.4 Nanomaterials 299 11.5 Conclusions 302 References 302 12 Nanotechnological Advancements in the Development of Antimicrobial PPE 309 List of Abbreviations 309 12.1 Introduction 310 12.2 Gloves 310 12.3 Face Masks and Respirators 311 12.4 Coveralls 313 12.5 Conclusions 315 References 315 13 Nanotechnology-Enabled Face Masks for Improved Medical Applications 321 List of Abbreviations 321 13.1 The Era of Infections and the Need for Improved Masks 322 13.2 Manufacturing Methods for Mask Fabrics 323 13.3 Common Masks and Respirators in Healthcare Systems 326 13.4 Nanofibers 328 13.5 Nanoporous Membranes 330 13.6 Nanocoatings 330 13.7 Advances in Nanotechnology-Based Face Masks During the COVID-19 Pandemic 332 13.8 Are They Ready to Use? 334 References 335 14 Nanocoated Medical Devices: Prospects and Challenges 343 List of Abbreviations 344 14.1 Introduction 344 14.2 Timeline of Nanocoating in Medicine 347 14.3 Nanocoating in Diagnostics and Disease Management 348 14.4 Nanocoating in Surgery 352 14.5 Nanocoated Implants 354 14.6 Risks and Challenges of Nanocoated Devices in Medicine 356 14.7 Future Perspectives of Nanocoated Devices 358 14.8 Conclusion 358 References 359 Index 363
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Subject Areas: Mechanical engineering & materials [TG]
