Multiple Sclerosis Therapeutics

An indispensable reference for researchers, research sponsors and neurologists interested in the rapidly developing field of multiple sclerosis therapeutics.

Jeffrey A. Cohen (Edited by), Richard A. Rudick (Edited by)

9780521766272, Cambridge University Press

Hardback, published 20 October 2011

770 pages, 150 b/w illus. 29 colour illus.
28.2 x 22.5 x 4.1 cm, 2.4 kg

This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors.

Part I. Introduction
Part II. Clinical Trial Methodology
Part III. Clinical Trials of Multiple Sclerosis Therapies
Part IV. Therapy in Clinical Practice.

Subject Areas: Therapy & therapeutics [MMZ], Neurology & clinical neurophysiology [MJN]