• Multiple Sclerosis; A Mechanistic View (Hardback) 9780128007631
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Multiple Sclerosis
A Mechanistic View

This is the first book on the market to examine the pathophysiology of multiple sclerosis, providing an invaluable resource for neurologists, neuroscientists, neurosurgeons, and others who need an in-depth understanding of the pathophysiology of this disease and its related disorders.

Alireza Minagar (Edited by)

9780128007631

Hardback, published 27 November 2015

538 pages
22.9 x 15.1 x 3.1 cm, 1 kg

Multiple Sclerosis: A Mechanistic View provides a unique view of the pathophysiology of multiple sclerosis (MS) and related disorders. As the only book on the market to focus on the mechanisms of MS rather than focusing on the clinical features and treatment of the disease, it describes the role of genetic and environmental factors in the pathogenesis of MS, the role of specific cells in the pathophysiology of the disease, and the pathophysiology of inflammatory and neurodegenerative disorders related to MS.

The book provides discussion of neurodegeneration and neuroregeneration, two critical emerging areas of research, as well as detailed discussion of the mechanisms of action of the approved and investigational drugs for treatment of MS and the emerging role of magnetic resonance spectroscopy (MRI) in investigations into MS.

It is the only book on the market to offer comprehensive coverage of the known mechanisms of MS and related diseases, and contains contributions from physicians and researchers who are worldwide experts in the field of study.

  1. Clinical manifestations of multiple sclerosis: An overview
  2. Novel Therapies for Multiple Sclerosis: A Mechanistic View
  3. Role of B cells in the pathogenesis of MS: Mechanisms of action
  4. Role of CD4+ T cells in the pathophysiology of MS
  5. GM-CSF in Central Nervous System Autoimmunity
  6. Role of cytokine-mediated crosstalk between T cells and non-immune cells in the pathophysiology of multiple sclerosis
  7. Vitamin D: role in pathogenesis of Multiple Sclerosis
  8. Role of genetic factors in pathogenesis of MS
  9. Neuropathology of multiple sclerosis
  10. Pathophysiology of acute disseminated encephalomyelitis
  11. Pathophysiology of experimental autoimmune encephalomyelitis
  12. Pathophysiology of optic neuritis
  13. Neurodegeneration and Remyelination in Multiple Sclerosis
  14. Mechanisms of action of Glatiramer Acetate in the treatment of multiple sclerosis
  15. Mechanism of Action of Interferon Beta in Treatment of Multiple Sclerosis
  16. Mechanisms of blood brain barrier disintegration in the pathophysiology of MS
  17. Mechanisms and potentials of Stem Cells in the treatment of Multiple Sclerosis: The unpaved path
  18. Role of neuroimaging in MS
  19. Pathophysiology of Lymphatic Drainage of the Central Nervous System. Implications for the Pathophysiology of Multiple Sclerosis

Subject Areas: Neurosciences [PSAN], Neurology & clinical neurophysiology [MJN], Child & developmental psychology [JMC]
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