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Multimodal Data Fusion for Bioinformatics Artificial Intelligence
Umesh Kumar Lilhore (Edited by), Lilhore (Author), Abhishek Kumar (Edited by), Narayan Vyas (Edited by), Sarita Simaiya (Edited by), Vishal Dutt (Edited by)
9781394269938, Wiley
Hardback, published 28 January 2025
416 pages
22.9 x 15.2 x 2.6 cm, 0.68 kg
Multimodal Data Fusion for Bioinformatics Artificial Intelligence is a must-have for anyone interested in the intersection of AI and bioinformatics, as it delves into innovative data fusion methods and their applications in ‘omics’ research while addressing the ethical implications and future developments shaping the field today. Multimodal Data Fusion for Bioinformatics Artificial Intelligence is an indispensable resource for those exploring how cutting-edge data fusion methods interact with the rapidly developing field of bioinformatics. Beginning with the basics of integrating different data types, this book delves into the use of AI for processing and understanding complex “omics” data, ranging from genomics to metabolomics. The revolutionary potential of AI techniques in bioinformatics is thoroughly explored, including the use of neural networks, graph-based algorithms, single-cell RNA sequencing, and other cutting-edge topics. The second half of the book focuses on the ethical and practical implications of using AI in bioinformatics. The tangible benefits of these technologies in healthcare and research are highlighted in chapters devoted to precision medicine, drug development, and biomedical literature. The book addresses a wide range of ethical concerns, from data privacy to model interpretability, providing readers with a well-rounded education on the subject. Finally, the book explores forward-looking developments such as quantum computing and augmented reality in bioinformatics AI. This comprehensive resource offers a bird’s-eye view of the intersection of AI, data fusion, and bioinformatics, catering to readers of all experience levels.
Preface xv 1 Advancements and Challenges in Multimodal Data Fusion for Bioinformatics AI 1 1.1 Introduction 1 1.2 Literature Review 4 1.3 Results and Discussion 8 2 Automated Machine Learning in Bioinformatics 13 2.1 Introduction 14 2.2 Need of Automated Machine Learning 16 2.3 Automated ML in Various Areas of Bioinformatics 19 2.4 Major Obstacles for Automated ML in Various Areas of Bioinformatics 23 2.5 Applications of Automated ML in Various Areas of Bioinformatics 24 2.6 Case Study 1 26 2.7 Conclusion and Future Directions 28 3 Data-Driven Discoveries: Unveiling Insights with Automated Methods 33 3.1 Introduction 34 3.2 Important Functions in Bioinformatics Include Data Mining and Analysis 36 3.3 Deep Learning in Bioinformatics 39 3.4 Challenges and Issues 42 3.5 Conclusion 45 4 Comparative Analysis of Conventional Machine Learning and Deep Learning Techniques for Predicting Parkinson's Disease 49 4.1 Introduction 50 4.2 Symptoms and Dataset for PD 52 4.3 Parkinson's Disease Classification Using Machine Learning Methods 53 4.4 Parkinson's Disease Classification Using DL Methods 57 4.5 Conclusion 59 5 Foundations of Multimodal Data Fusion 67 5.1 Introduction 68 5.2 What is Multimodal Data Fusion in Bioinformatics AI? 69 5.3 Types of Data Modalities in Bioinformatics 70 5.4 Challenges and Considerations in Multimodal Data Fusion 73 5.5 Foundational Principles of Data Fusion 77 5.6 Machine Learning and Deep Learning Techniques for Multimodal Data Fusion 80 5.7 Feature Representation and Fusion 84 5.8 Applications in Bioinformatics AI 88 5.9 Evaluation Metrics and Validation Strategies 92 5.10 Evaluation Metrics 93 5.11 Approval Techniques 94 5.12 Ethical and Legal Considerations 95 5.13 Future Directions and Challenges 95 5.14 Conclusion 96 6 Integrating IoT, Blockchain, and Quantum Machine Learning: Advancing Multimodal Data Fusion in Healthcare AI 103 6.1 Introduction 104 6.2 Internet of Things (IoT) in Healthcare 107 6.3 Blockchain Technology in Healthcare 111 6.4 Quantum Machine Learning in Healthcare 113 6.5 Integration of IoT, Blockchain, and Quantum Machine Learning in Healthcare 116 6.6 Ethical and Regulatory Considerations in Healthcare Technology 118 6.7 Challenges and Future Directions in Healthcare Technology Integration 119 6.8 Results and Discussion 121 6.9 Conclusion 122 7 Integrating Multimodal Data Fusion for Advanced Biomedical Analysis: A Comprehensive Review 127 7.1 Introduction 128 7.2 Multimodal Biomedical Analysis 130 7.3 Challenges in Data Fusion 132 7.4 Deep Learning Methods for Data Fusion 134 7.5 Case Studies and Applications 136 7.6 Future Directions 139 7.7 Conclusion 142 8 Machine Learning Approaches for Integrating Imaging and Molecular Data in Bioinformatics 147 8.1 Introduction 148 8.2 Background and Motivation 152 8.3 Machine Learning Basics 154 8.4 Approaches for Data Integration 156 8.5 Machine Learning Techniques for Imaging and Molecular Data 167 8.6 Applications 168 8.7 Challenges and Future Directions 170 8.8 Case Studies 172 8.9 Conclusion 174 9 Time Series Analysis in Functional Genomics 179 9.1 Introduction 180 9.2 Foundations of Time Series Analysis in Functional Genomics 182 9.3 Methodologies for Time Series Analysis 186 9.4 Applications of Time Series Analysis in Functional Genomics 194 9.5 Integration with Multimodal Data 196 9.6 Conclusion 199 10 Review of Multimodal Data Fusion in Machine Learning: Methods, Challenges, Opportunities 205 10.1 Introduction 206 10.2 Related Work 208 10.3 Multimodal and Data Fusion 211 10.4 Applications, Opportunities, and Challenges 216 10.5 Conclusion and Future Directions 219 11 Recent Advancement in Bioinformatics: An In-Depth Analysis of AI Techniques 227 11.1 Introduction 228 11.2 AutoMLDL Methods 230 11.3 Application of AutoMLDL in Bioinformatics 233 11.4 Advanced Algorithm in AutoMLDL for Bioinformatics 238 11.5 Security and Privacy Issues in AutoMLDL 240 11.6 Conclusion and Future Works 241 12 Future Directions and Emerging Trends in Multimodal Data Fusion for Bioinformatics 247 12.1 Introduction 248 12.2 Foundational Concepts 253 12.3 Current State of Multimodal Data Fusion in Bioinformatics 258 12.4 Emerging Trends in Data Fusion 260 12.5 Algorithms 266 12.6 Future Directions 272 12.7 Case Studies and Applications 274 12.8 Challenges and Opportunities 276 12.9 Conclusion 278 13 Future Trends in Bioinformatics AI Integration 283 13.1 Introduction 284 13.2 What Is Multimodal Data Fusion? 285 13.3 Types of Multimodal Data in Bioinformatics 286 13.4 Challenges in Multimodal Data Fusion 288 13.5 Multimodal Data Integration Approaches 288 13.6 Feature Representation and Selection 289 13.7 Integration of Omics Data 290 13.8 Clinical Applications 291 13.9 Imaging Data Fusion 292 13.10 Biological Network Integration 294 13.11 Applications in Precision Medicine 295 13.12 Computational Tools and Resources 297 13.13 Future Directions and Challenges 298 13.14 Conclusion 300 14 Emerging Technologies in IoM: AI, Blockchain and Beyond 305 14.1 Introduction 306 14.2 Artificial Intelligence (AI) in Healthcare 307 14.3 Blockchain in the Medical Landscape 309 14.4 Benefits of Using Technologies in IoM 311 14.5 Integration of Cutting-Edge Technologies 314 14.6 Beyond AI and Blockchain: Exploring Additional Technologies 315 14.7 Ethical Considerations in Implementing Emerging Technologies 317 14.8 Conclusion 319 15 Natural Language Processing in Biomedical Literature 323 15.1 Introduction 324 15.2 History 326 15.3 Theoretical Foundation: Natural Language Processing in Scientific Writing 327 15.4 Sources of Diversity in Biomedical Literature's Natural Language Processing 330 15.5 Disagreement and Conflict 332 15.6 Natural Language Processing Trends and Patterns in Biomedical Literature 332 15.7 Natural Language Processing's Useful Applications in Biomedical Literature 334 15.8 Future Prospects of NLP in Biomedical Literature 336 15.9 Conclusion 337 16 Biomedical Research Enrichment Through Sentiment Analysis in Patient Feedback: A Natural Language Processing Approach 341 16.1 Introduction 342 16.2 Applications of NLP 346 16.3 Background Studies in Sentimental Analysis 353 16.4 Processes Needed for Sentimental Analysis 359 16.5 Conclusion 369 Acknowledgment 370 References 370 About the Editors 375 Index 377
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Subject Areas: Biology, life sciences [PS]
