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Multidisciplinary Microfluidic and Nanofluidic Lab-on-a-Chip
Principles and Applications
A practical guide on how to design, analyze, fabricate, and test microfluidic devices and systems for a wide variety of applications
Xiujun (James) Li (Edited by), Chaoyong Yang (Edited by), Paul C. H. Li (Edited by)
9780444594327, Elsevier Science
Hardback, published 23 September 2021
484 pages
23.4 x 19 x 2.9 cm, 1 kg
Multidisciplinary Microfluidic and Nanofluidic Lab-on-a-Chip: Principles and Applications provides chemists, biophysicists, engineers, life scientists, biotechnologists, and pharmaceutical scientists with the principles behind the design, manufacture, and testing of life sciences microfluidic systems. This book serves as a reference for technologies and applications in multidisciplinary areas, with an emphasis on quickly developing or new emerging areas, including digital microfluidics, nanofluidics, papers-based microfluidics, and cell biology. The book offers practical guidance on how to design, analyze, fabricate, and test microfluidic devices and systems for a wide variety of applications including separations, disease detection, cellular analysis, DNA analysis, proteomics, and drug delivery. Calculations, solved problems, data tables, and design rules are provided to help researchers understand microfluidic basic theory and principles and apply this knowledge to their own unique designs. Recent advances in microfluidics and microsystems for life sciences are impacting chemistry, biophysics, molecular, cell biology, and medicine for applications that include DNA analysis, drug discovery, disease research, and biofluid and environmental monitoring.
Part I: Fundamentals of microfluidic/nanofluidic lab-on-a-chip 1. Micromachining Methods 2. Micromachining of silicon, glass devices 3. Micromachining of polymers 4. Fabrication of paper-based microfluidic devices 5. Biocompatibility and surface modifications 6. Systems interconnect and world-to-chip interface 7. Microfluidic Flow control Part II: New Emerging Techniques 8. Droplet microfluidics 9. Closed-channel Droplet generation 10. Open-format Digital microfluidics 11. Nanofluidics 12. Nanofabrication 13. Characteristics of nanofluidics Part III: Applications 14. Applications to Cell Biology 15. Manipulation of cells 16. Cellular measurements and analysis 17. Single-cell analysis 18. 3D cell culture 19. Organs-on-a-chip 20. Applications to Nuclei Aids Analysis 21. Nucleic acids extraction and purification 22. Nucleic acids amplification 23. Forensic DNA typing 24. Microarray DNA chips 25. Applications to proteins analysis 26. Immunoassay 27. Protein separation 28. Enzymatic analysis 29. Proteomics 30. Applications to global health 31. Low-cost Paper-based diagnosis devices 32. Field diagnosis 33. Other applications 43. Environmental analysis 44. Forensic analysis 45. Small ions and molecules analysis 46. Microreacter 47. Perspective 48. Instrument/device commercialization
Subject Areas: Industrial chemistry [TDC], Fluid mechanics [PHDF]
