mRNA Metabolism & Post-Transcriptional Gene Regulation

Joe B. Harford (Edited by), Harford (Author), David R. Morris (Edited by)

9780471142065, Wiley

Paperback / softback, published 7 April 1997

368 pages
26.1 x 18.5 x 2.3 cm, 0.907 kg

Hinsichtlich der Steuerung der Genexpression wurde bisher meist die Regulation der RNA-Synthese (Transkription) betrachtet. Erst vor relativ kurzer Zeit erkannte man, daß wichtige Regelmechanismen erst nach der Transkription einsetzen. Das Buch bietet den ersten verfügbaren vollständigen Überblick über dieses aktuelle Forschungsgebiet.

Partial table of contents:

RNA Structure (E. Puglisi & J. Puglisi).

Transcription and Transcriptional Control: An Overview (I. Olave,et al.).

Constitutive and Alternative mRNA Splicing (S. Bernstein & D.Hodges).

mRNA Polyadenylation: Functional Implications (E. Baker).

RNA Export from the Nucleus (L. Maquat).

The Intracellular mRNA Sorting System: Postal Codes, Zip Codes,Mail Bags and Mail Boxes (O. Steward & R. Singer).

The Fundamentals of Translation Initiation (H. Huang & T.Donahue).

Mechanisms of mRNA Turnover in Eukaryotic Cells (S. Tharun & R.Parker).

Control of mRNA Decay in Plants (A. van Hoof & P. Green).

mRNA Metabolism and Cancer (M. Korth & M. Katze).

Translational Regulation in Animal Virus-Infected Cells (R.Schneider).

RNA Decay by the Interferon-Regulated 2-5A System as a Host DefenseAgainst Viruses (R. Silverman & N. Cirino).

Control of mRNA Stability During Herpes Simplex Virus Infection (G.Read).

Regulation of mRNA Expression in HIV-1 and Other Retroviruses (B.Felber).

Index.

Subject Areas: Biology, life sciences [PS]