Monoamine Oxidases and their Inhibitors

Following the newly published positive Phase III delayed study (ADAGIO) with rasagiline in Parkinson's Disease, this volume presents 15 papers on various aspects of Monoamine Oxidase and its Inhibitors.

Moussa Youdim (Volume editor), Peter Riederer (Volume editor)

9780123864673, Elsevier Science

Hardback, published 17 November 2011

320 pages
22.9 x 15.1 x 2.4 cm, 0.55 kg

"Invaluable reading." --NATURE

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. In this volume, invited experts provide authoritative reviews on various aspects of Monoamine Oxidase and its Inhibitors.

1. Pharmacology of selegiline
2. Xray crystal structure of MAO A and B
3. Structures of MAO A and B. Deficit of MAO clinical implications
4. Pharmacology of MAO and B inhbitors and Cheese reaction
5. Safinamide. Novel reversible MAO B.
6. Ladostigil amd M30in PD and AD neuroprotection and neurorestoration.
7. Rasagline and disease modification
8. Rasagiline and Parkinson's disease and neuroprotection
9. Multimodal drugs and their future for AD and PD
10. Molecular mechanism of selegiline as a neuroprotectiev drug
11. Kinetics of monoamine oxidase
12. novel MAO inhibitors
13. Rasagiline in Parkinson’s disease

Subject Areas: Neurosciences [PSAN], Pharmacology [MMG], Neurology & clinical neurophysiology [MJN], Cytology [MFCC]