Molecular Physiology of Growth

This book presents an up-to-date review of molecular regulation of growth in animals.

P. T. Loughna (Edited by), J. M. Pell (Edited by)

9780521471107, Cambridge University Press

Hardback, published 10 October 1996

184 pages, 38 b/w illus. 2 tables
22.9 x 15.2 x 1.4 cm, 0.44 kg

"This book is a great resource for beginners as well as those who already use this technique, because each chapter contains its own methods section." James Konopka, The Quarterly Review of Biology

How do hormones and growth factors regulate animal growth in the developing embryo and after injury? What processes at the molecular level determine the growth patterns of different tissues? In this diverse synthesis of recent research the regulation of growth in response to environmental and genetic stimuli is discussed at the level of the animal, tissues and cells. Contrasts are drawn between regulation in foetal and adult tissues, and in different tissues such as the CNS, bone and muscle. Functional chapters focus on the molecular links between mechanical tension and muscle growth, for example, while other chapters review the roles of specific molecules such as growth hormone. This state-of-the-art review will be of significant interest to graduate students and research scientists in the fields of animal growth, endocrinology and cell biology.

1. Role of growth hormone in growth regulation D. J. Flint, K. Akinsaya, P. J. Crilly, P. Johnston and D. Wynick
2. Insulin-like growth factor-1 and its binding proteins: role in postnatal growth J. M. Pell and J. Glassford
3. Growth factor interactions in epiphyseal chondrogenesis D. J. Hill
4. Developmental changes in the CNS response to injury: growth factor and matrix interactions A. Logan
5. The role of transforming factor ß during cardiovascular development M. C. Dickson, J. S. Martin and R. J. Ackhurst
6. Tenascin: an extracellular matrix protein associated with bone growth E. J. Mackie and S. Ramsey
7. Compartmentation of protein synthesis, mRNA targeting and c-myc expression during mucle hypertrophy and growth J. Hesketh
8. The role of mechanical tension in regulating muscle growth and phenotype P. T. Loughna and C. Brownson
9. The prenatal influence on postnatal muscle growth N. C. Stickland and C. M. Dwyer
10. Genomic imprinting and intrauterine growth retardation G. E. Moore, P. R. Bennett, Z. Ali, R. U. Khan and J. I. Vaughan.

Subject Areas: Animal physiology [PSVD], Developmental biology [PSC]