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Molecular Mechanisms that Orchestrate the Assembly of Antigen Receptor Loci

The latest in this series provides cutting-edge reviews in the field of immunology, focusing on how antigen receptors are synthesized in B and T lymphocytes.

Cornelis Murre (Volume editor)

9780128032961

Hardback, published 19 October 2015

454 pages
22.9 x 15.1 x 2.8 cm, 0.81 kg

Molecular Mechanisms That Orchestrate the Assembly of Antigen Receptor Loci, the latest volume in the Advances in Immunology series focuses on the generation of an effective immune response to invading pathogens

As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes.

  1. Regulation and Evolution of the RAG Recombinase
    Grace Teng and David G. Schatz
  2. Chromatin Interactions in the Control of Immunoglobulin Heavy Chain Gene Assembly
    Gita Kumari and Ranjan Sen
  3. Spatial Regulation of V-(D)J Recombination at Antigen Receptor Loci
    Anja Ebert, Louisa Hill and Meinrad Busslinger
  4. Long Range Regulation of V(D)J Recombination
    Charlotte Proudhon, Bingtao Hao, Ramya Raviram, Julie Chaumeil and Jane A. Skok
  5. Dynamic Control of Long-range Genomic Interactions at the Immunoglobulin ? Light Chain Locus
    Claudia Ribeiro de Almeida, Rudi W. Hendriks and Ralph Stadhouders
  6. Regulation of Tcrb Gene Assembly by Genetic, Epigenetic, and Topological Mechanisms
    Kinjal Majumder, Craig H. Bassing and Eugene M. Oltz
  7. Chromatin Dynamics and the Development of the TCRa and TCRd  Repertoires
    Zachary Carico and Michael S. Krangel
  8. Long-range Control of V(D)J Recombination & Allelic Exclusion: Modeling Views
    Pernelle Outters, Sébastien Jaeger, Nancy Zaarour and Pierre Ferrier

Subject Areas: Cellular biology [cytology PSF], Molecular biology [PSD], Immunology [MJCM]

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