Molecular Biology of Protein Folding, Part A

Recent research shows that many unrelated diseases ? Alzheimer's disease, cystic fibrosis, mad cow disease and many forms of cancer ? result from protein folding gone wrong. This volume pulls together compelling and timely reviews to aid researchers in understanding the concepts of protein folding and how protein folding can be monitored and studied.

P. Michael Conn (Edited by)

9780123745941, Elsevier Science

Hardback, published 19 December 2008

288 pages
22.9 x 15.1 x 2.3 cm, 0.55 kg

The importance of protein folding has been recognized for many years. It is the underlying etiology in a large number of human diseases and it appears to be a novel method for cellular regulation of the expression of newly translated proteins. These volumes (Parts A & B) address this important topic. As a volume in Progress in Nucleic Acid Research and Molecular Biology, this book provides the latest information on the expanding research being conducted on protein folding.

1. Stability and design of alpha-helical peptides - Andrew Doig

2. Under-wrapped protein folds in disease and epigenetic change - Ariel Fernandez

3. Self-organizing dynamics in protein folding - Bernard S. Gerstman

4. Diffusive models for protein folding - Stephen J Hagen

5. Toward reliable simulations of protein folding, misfolding and aggregation - Ulrich HE Hansmann

6. Single-molecule fluorescence studies of protein folding - Gilad Haran

7. Algorithms for protein folding - Sorin Istrail

8. Use of protein engineering techniques to elucidate protein folding pathways - Sophie Jackson

9. The kinetic stabilities of wild-type and disease-associated mutants of aromatic amino acid hydroxylases. Effect of natural chaperone ligand - Aurora Martinez

10. Chaperone-assisted protein folding in the endoplasmic reticulum - Maurizio Molinari

11. Protein folding over marginal barriers: ensembles, dynamics and stochastics - Victor Munoz

Subject Areas: Molecular biology [PSD], Proteins [PSBC], Biochemistry [PSB], Biophysics [PHVN], Medicine [M]