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Modelling Methodology for Physiology and Medicine
State of the art in mathematical modeling methodology for application to physiology and medicine
Ewart Carson (Author), Claudio Cobelli (Author)
9780124115576
Hardback, published 12 December 2013
588 pages
22.9 x 15.1 x 3.3 cm, 0.96 kg
Modelling Methodology for Physiology and Medicine, Second Edition, offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modeling methodology that is widely applicable to physiology and medicine. The second edition, which is completely updated and expanded, opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. The focus of Modelling Methodology for Physiology and Medicine, Second Edition, is the methodology that underpins good modeling practice. It builds upon the idea of an integrated methodology for the development and testing of mathematical models. It covers many specific areas of methodology in which important advances have taken place over recent years and illustrates the application of good methodological practice in key areas of physiology and medicine. It builds on work that the editors have carried out over the past 30 years, working in cooperation with leading practitioners in the field.
1. An introduction to modelling methodology 2. Control in Physiology and Medicine 3. Deconvolution4. A priori identifiability of physiological parametric models 5. Parameter estimation 6. New Trends in nonparametric linear system identification 7. Population Modelling 8. Systems Biology 9. Genomic Regulatory Networks 10. Tracer experiment design for metabolic fluxes estimation in steady and nonsteady state 11. Physiological modelling of positron emission tomography images 12. Downstream from Heart Left Ventricle: Aortic Impedance Interpretation by Lumped- and Tube-load Models13. Mathematical modelling of pulmonary gas exchange 14. Acid- base modelling 15. Insulin modelling 16. Glucose modelling 17. Blood-tissue exchange modelling 18. Stochastic modelling of physiological systems 19. Tumour growth modelling for drug development 20. Modelling cardiac biomechanics 21. Finite element modelling in musculoskeletal biomechanics 22. Probabilistic modelling with Bayesian networks 23. Modelling for synthetic biology 24. Mathematical models for computational neuroscience
Subject Areas: Mathematical modelling [PBWH], Biomedical engineering [MQW], Physiology [MFG]
