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Modeling Neuropsychiatric Disorders in Laboratory Animals
Focuses on the rationale and theory of using animal behavior, both pathological and normal, to understand the neural underpinnings of neuropsychiatric disorders
Kurt Leroy Hoffman (Author)
9780081000991, Elsevier Science
Hardback, published 18 September 2015
324 pages
22.9 x 15.1 x 2.4 cm, 0.64 kg
Modeling Neuropsychiatric Disorders in Laboratory Animals serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders. The text focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders. Chapters contain discussions on both classical and modern views on the validation of animal models for neuropsychiatric disorders, also discussing the utility of endophenotypes in modeling neuropsychiatric disease. Subsequent chapters deal with four specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders. Final sections discuss the future for the development, validation, and use of animal models in basic and preclinical research.
Subject Areas: Animal pathology & diseases [PSVL], Veterinary medicine: laboratory animals [MZF], Psychiatry [MMH], Neurology & clinical neurophysiology [MJN], Medical laboratory testing & techniques [MBGL], Physiological & neuro-psychology, biopsychology [JMM]
