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Mitochondrial Metabolism
An Approach to Disease Management

A complete reference on the paths to mitotherapy from pharmacology, toxicology and biochemistry perspectives

Jalal Pourahmad (Edited by), Mohsen Rezaei (Edited by)

9780128224168, Elsevier Science

Paperback, published 29 July 2021

316 pages, 80 illustrations (30 in full color)
22.9 x 15.2 x 2.1 cm, 0.5 kg

Mitochondrial Metabolism: An Approach for Disease Management covers mitotherapy from three combined perspectives, Pharmacology, Toxicology and Biochemistry. After an introduction from world-renowned experts, the book's chapters cover the balancing role in reduction/oxidation mitochondria play, mitochondria as targets for therapeutics through its metabolism, mitochondrial contributions to the cell death process, mitochondrial response to environmental toxicants, the mitochondrial role in aging, the impact of calorie restrictive diets, new advances in the identification of altered mitochondria associated signaling pathways in carcinogenesis, and much more.

This book provides bioscientists new horizons to realize the importance of mitochondria in present-day research on therapies dealing with mitochondria associated chronic diseases, including diabetes, cancer and neurodegenerative disorders.

1. Mitochondria as balancers of reduction/oxidation for intracellular environment 2. Mitochondria as biosynthetic centers and targeted therapeutics 3. Mitochondrial contribution to cell death 4. Mitochondrial response to environmental toxicants 5. Updates on mitochondria, calorie restriction and aging 6. Mitochondrial metabolism and carcinogenesis 7. Mitochondria and cancer therapy 8. Mitochondrial metabolism in diabetes 9. Mitochondrial abnormalities in neurological disorders 10. Mitochondrial abnormalities in psychological disorders 11. Mitotherapy, an attractive avenue for the future medicine

Subject Areas: Cellular biology [cytology PSF]

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