Microbial Metabolism and Disease

Investigates microbial metabolic pathways and their impact upon various human diseases and conditions

Elena L. Paley (Author)

9780323884457

Paperback, published 18 March 2021

306 pages, 80 illustrations (30 in full color)
23.4 x 19 x 2 cm, 0.61 kg

Microbiome Metabolic Pathways and Disease provides insight into the interaction of microbial metabolic pathways in the human body and the impact these can have on a variety of diseases. By analyzing these pathways the book seeks to investigate how these metabolic processes can be targeted and manipulated in order to treat various disorders and diseases. Topics covered in the book include microbial shikimate pathways, protein biosynthesis, tryptophan metabolites, microbiome metabolic engineering, fecal microbiota transplantation, and virulence factors. Additionally, a variety of conditions are covered, such as disorders associated with metabolic syndromes, serotonin syndromes, Alzheimer’s disease, and Covid-19, providing a detailed overview of how metabolic pathways of microbiome can impact health and disease in the human body.

1. Naturally occurring affectors of initial step of protein biosynthesis2. Physicochemical, biochemical and cell biology properties and byproducts of tryptamine and other “trace? amines3. Tryptophan metabolites and biogenic amines in physical exercises4. Tryptamine in inflammation and regulation of gene transcription5. Genes encoding mammalian, plant and microbial aromatic amino acid decarboxylase6. Decarboxylases producing tryptamine and other biogenic amines in human microbiome7. Microbial shikimate pathway in diseases8. Biogenic amines in fasting, feeding and stress conditions9. Metabolites of shikimate and tryptophan pathways in Corona virus disease (COVID-19)10. Virulence factors11. Relation of human gut Alzheimer’s disease associated sequence (ADAS) with shikimate pathway metabolites12. Benefits of using fecal microbiota transplantation as treatment have been controversial13. Shikimate pathway enzymes in human microbiome14. Tryptophan operon in human microbiome and inhibitors of tryptophan operon enzymes15. Antibodies to tryptamines16. Cell death in Alzheimer's disease brain and tryptamine-treated cells

Subject Areas: Molecular biology [PSD]