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Micro- and Nanotechnology in Vaccine Development
Ideal for those who need to familiarize themselves quickly with the broad spectrum of vaccines available, this comprehensive book presents a focused overview of the impact of micro- and nanotechnology on vaccine development, drug delivery, and lipids
Mariusz Skwarczynski (Edited by), Istvan Toth (Edited by)
9780323399814, Elsevier Science
Hardback, published 3 October 2016
460 pages
23.4 x 19 x 2.9 cm, 1.11 kg
"Overall, all the chapters uniquely illustrate various advantageous opportunities that micro- and nanotechnologies may contribute to the development of more precise and effective, as well as safe and economical vaccines without omitting risks and challenges that are still given today. Therefore, this book is a suitable reference for further research on vaccine development in a dawning era of nanotechnology in vaccination and immunotherapy." --ChemMedChem
This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles.
Overview of immune system.
Innate immunity and special role of antigen presenting cells.
Immunity and size.
Introduction to the vaccines.
Current challenges in vaccine development.
Growing role of nanotechnology
Nanotechnology in medical research
Nanoparticle based peptide vaccines
Liposome as nano- and microvaccines
Lipid in peptide vaccine (excluding liposomes)
Nanoadjuvants for peptide based vaccines
Nanopatches for vaccine delivery
Oral vaccine delivery
Nano- and microtechnology in skin delivery of vaccines
Nasal vaccine delivery
Nanoparticles for cancer targeting vaccines by
polymer based nanovaccines
Lipidic microparticles for vaccine delivery
Polymeric microparticles for vaccine delivery
Subject Areas: Chemical engineering [TDCB], Immunology [MJCM], Public health & preventive medicine [MBN]
