Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms

Covers the design and fabrication of micro and nano systems and their application to biophysical studies of cells and small organisms.

Xinyu Liu (Edited by), Yu Sun (Edited by)

9780128239902, Elsevier Science

Paperback, published 17 August 2021

404 pages, Approx. 160 illustrations
23.5 x 19 x 2.6 cm, 0.86 kg

Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms provides a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanical systems (MEMS) and microfluidic devices to robotic micro-nanomanipulation systems. These biophysical studies range from cell mechanics to the neural science of worms and Drosophila. This book will help readers understand the fundamentals surrounding the development of these tools and teach them the most recent advances in cellular and organismal biophysics enabled by these technologies.

1. Micro systems for probing cellular forces and cellular mechanical properties 2. Force-sensing micropillar arrays for cell mechanics and mechanobiology 3. Vertical nanostructures for probing live cells 4. Probing tissue mechanics at the cellular length-scale in cancer microenvironments 5. Advanced microfluidic devices for cell electroporation and manipulation 6. High-throughput three-dimensional cellular platforms for screening biophysical microenvironmental signals 7. Acoustofluidic technology for cell biophysics 8. Microfluidic devices for neutrophil migration studies 9. Field-controlled micro-nano manipulations and micro-nano robots 10. Robotic optical tweezers for cell biophysics 11. Robotic and microfluidic systems for single cell injection 12. Biophysical phenotyping of C. elegans in a microfluidic chip for high-throughput drug screening 13. Microfluidic devices for imaging and manipulation of C. elegans 14. Micro systems for the study of behavioral responses of C. elegans to various physical and chemical stimuli 15. Microfluidic devices to study the effect of electric fields on C. elegans and Danio rerio 16. Force-controlled robotic systems for mechanical stimulation of Drosophila larvae

Subject Areas: Other manufacturing technologies [TDP], Biotechnology [TCB], Biomedical engineering [MQW], Personal & public health [MBNH], Biotechnology industries [KNDH1]