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Metabolomics in Food and Nutrition
Bart C Weimer (Edited by), Carolyn Slupsky (Edited by)
9781845695125, Elsevier Science
Hardback, published 31 October 2013
264 pages
23.3 x 15.6 x 2.2 cm, 0.55 kg
Metabolomics enables valuable information about the biochemical composition of foods to be rapidly obtained. Since the biochemical profile of food largely determines key food properties such as flavour and shelf life, the information gained using metabolomics-based methods will enable greater control of food quality and also help to determine the relationship between diet and health. Metabolomics in food and nutrition provides an overview of their current and potential use in the food industry.
Part one reviews equipment, methods and data interpretation in metabolomics including the use of nuclear magnetic resonance (NMR), statistical methods in metabolomics, and metabolic reconstruction databases and their application to metabolomics research. Part two explores applications of metabolomics in humans, plants and food. Chapters discuss metabolomics in nutrition, human samples for health assessments, and current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications. Further chapters highlight metabolomic analysis of plants and crops, metabolomics for the safety assessment of genetically modified (GM) crops, and applications of metabolomics in food science including food composition and quality, sensory and nutritional attributes.
With its distinguished editors and team of expert contributors, Metabolomics in food and nutrition is a technical resource for industrial researchers in the food and nutrition sectors interested in the potential of metabolomics methods and academics and postgraduate students working in the area.
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Woodhead Publishing Series in Food Science, Technology and Nutrition
Introduction
Part I: Equipment, methods and data interpretation in metabolomics
Chapter 1: Equipment and metabolite identification (ID) strategies for mass-based metabolomic analysis
Abstract:
1.1 Introduction
1.2 Liquid chromatography
1.3 Gas chromatography
1.4 Mass spectrometry technologies
1.5 Analytical systems
1.6 Compound identification (ID) approaches
1.7 Databases for tracking and interconnections
1.8 Future trends
1.9 Sources of further information and advice
1.10 Acknowledgments
1.11 References
Chapter 2: Metabolomics using nuclear magnetic resonance (NMR)
Abstract:
2.1 Introduction
2.2 Experimental design and preparation
2.3 Experimental process and analysis
2.4 Current applications and future trends
2.5 References
2.6 Appendix: abbreviations
Chapter 3: Statistical methods in metabolomics
Abstract:
3.1 Introduction
3.2 Exploratory/visual approaches
3.3 Inferential approaches
3.4 Multiple hypothesis testing
3.5 Ensemble learning approaches
3.6 Conclusion
3.7 References
3.8 Appendix: software packages used
Chapter 4: Metabolic reconstruction databases and their application to metabolomics research
Abstract:
4.1 Introduction
4.2 Overview of Pathway/Genome Database (PGDB) construction
4.3 Querying PGDBs
4.4 Metabolomics applications
4.5 Sources of further information and advice
4.6 Conclusion
4.7 Acknowledgments
4.8 References
Part II: Applications of metabolomics in humans, plants and food
Chapter 5: Human samples for health assessments
Abstract:
5.1 Introduction
5.2 Sample collections and biobanks
5.3 Variation in metabolite profiles of human biofluids and tissues
5.4 Standards for metabolomic studies
5.5 Conclusions and future trends
5.6 References
Chapter 6: Metabolomics in nutrition
Abstract:
6.1 Introduction
6.2 Epidemiological studies and biomarkers of food intake
6.3 Diet and metabolic syndrome
6.4 The role of intestinal microbiota in nutrition
6.5 Perspectives in nutrition research
6.6 Future trends
6.7 References
Chapter 7: Current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications
Abstract:
7.1 Introduction
7.2 Analysis of human milk oligosaccharides (HMOs)
7.3 Applications of HMO analysis
7.4 Conclusion
7.5 References
Chapter 8: Metabolomic analysis of plants and crops
Abstract:
8.1 Introduction
8.2 Metabolomic studies on selected Poaceae species
8.3 Metabolomic studies on selected Solanaceae species
8.4 Metabolomic studies on selected Fabaceae species
8.5 Metabolomic studies on selected Brassicaceae and Lamiaceae species
8.6 Plant/crop metabolome databases
8.7 Future trends
8.8 References
Chapter 9: Metabolomics for the safety assessment of genetically modified (GM) crops
Abstract:
9.1 Introduction
9.2 Solanaceous crops
9.3 Cereal crops
9.4 Other crops
9.5 Metabolomics as part of a regulatory risk assessment procedure for the development and evaluation of genetically modified (GM) crops
9.6 Metabolomics and GM food safety: future trends
9.7 Acknowledgements
9.8 References
Chapter 10: Applications of metabolomics in food science: food composition and quality, sensory and nutritional attributes
Abstract:
10.1 Introduction
10.2 Metabolomics for compound identification: authentication and pathogen detection
10.3 Metabolomics for predicting sensory attributes
10.4 Metabolomics and food processing and safety
10.5 Conclusion
10.6 References
Index
Subject Areas: Food & beverage technology [TDCT]
