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Mesenchymal Stem Cell Derived Exosomes
The Potential for Translational Nanomedicine
Understanding the potential for MSC-derived exosomes in nano-based therapies
Yaoliang Tang (Author), Buddhadeb Dawn (Author)
9780128001646, Elsevier Science
Hardback, published 6 November 2015
288 pages
22.9 x 15.1 x 2.3 cm, 0.61 kg
Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool.
1: Insights into the Mechanism of Exosome Formation and Secretion 2: An Overview of the Proteomic and miRNA Cargo in MSC Derived Exosomes 3: Exosome Function in miRNA-Mediated Paracrine Effects 4: Current Methods in Purification of MSC-Derived Exosomes 5: Stem Cell Extracellular Vesicles: A Novel Cell-Based Therapy for Cardiovascular Diseases 6: The Cardioprotection of Mesenchymal Stem Cell and Anti-Apoptotic microRNA Transfer Through Exosomes 7: Engineered/Hypoxia-Preconditioned MSCs Derived Exosome: Potential Therapeutic Applications 8: Exosome-Based Translational Nanomedicine: The Therapeutic Potential for Drug Delivery 9: Effect of Exosomes from Mesenchymal Stem Cells on Angiogenesis 10: Exosomes for Bone Diseases 11: Diagnostic and Prognostic Applications of MicroRNA-Abundant Circulating Exosomes
Subject Areas: Molecular biology [PSD], Immunology [MJCM], Medical diagnosis [MJA], Personal & public health [MBNH], Biotechnology industries [KNDH1]
