Membrane Structural Biology
With Biochemical and Biophysical Foundations

An updated edition on membrane biology, providing new high resolution structures of membrane proteins and insights into how they function.

Mary Luckey (Author)

9781107030633, Cambridge University Press

Hardback, published 24 February 2014

423 pages, 184 b/w illus. 610 colour illus. 16 tables
28.6 x 22 x 2.5 cm, 1.44 kg

This textbook provides a strong foundation and a clear overview for students of membrane biology and an invaluable synthesis of cutting-edge research for working scientists. The text retains its clear and engaging style, providing a solid background in membrane biochemistry, while also incorporating the approaches of biophysics, genetics and cell biology to investigations of membrane structure, function and biogenesis to provide a unique overview of this fast-moving field. A wealth of new high resolution structures of membrane proteins are presented, including the Na/K pump and a receptor-G protein complex, offering exciting insights into how they function. All key tools of current membrane research are described, including detergents and model systems, bioinformatics, protein-folding methodology, crystallography and diffraction, and molecular modeling. This comprehensive and up-to-date text, emphasising the correlations between membrane research and human health, provides a solid foundation for all those working in this field.

Dedication
Preface
1. Introduction
2. The diversity of membrane lipids
3. Tools for studying membrane components
4. Proteins in or at the bilayer
5. Bundles and barrels
6. Functions and families
7. Protein folding and biogenesis
8. Diffraction and simulation
9. Membrane enzymes
10. Membrane receptors
11. Transporters
12. Channels
13. Electron transport and energy transduction
14. In pursuit of complexity
Appendix I. Abbreviations
Appendix II. Single-letter codes for amino acids
Index.

Subject Areas: Computer science [UY], Data capture & analysis [UNC], Molecular biology [PSD], Biochemistry [PSB], Biology, life sciences [PS], Data analysis: general [GPH]