I. Setting the scene and introductory chapters

1. How medical cannabis may influence the future of medicine Martha Rosenthal

2. Medical cannabis and cannabinoids: how best to extract components from plant material Roberta Costi

3. Medicinal usage of cannabis and its impact on mental health among cancer patients and survivors Nicolas Hernandez Ortega, Ye Chen, Jessica Y. Islam, Diane Rodriguez, Marlene Camacho-Rivera and Denise Christina Vidot

4. Cannabis sativa as a traditional phytomedicine: a new narrative covering different countries Md Nasir Ahmed, Tridib Paul, Md. Nur Kabidul Azam, Rownak Jahan and Mohammed Rahmatullah

5. Medical use of cannabis in the middle east Bader Hamza Shirah, Mohammed Ahmed and Ruba Saleh

6. What medicinal cannabis is used for: a focus on Canada Dean T. Eurich, Cerina Lee and Jason Dyck

7. New York perspectives of medical cannabis laboratory analysis Lingyun Li, Stacey Chmura, Christopher Judd and Bryan C. Duffy

8. Potential roles of epigenetic memory on the quality of clonal cannabis plants: Content and profile of secondary metabolites Mohsen Hesami and Max Jones

9. Aberrant use of medicinal cannabis: theoretical and empirical considerations Daniel Feingold

10. Profile of older users of medical cannabis and cannabinoids Joshua Brown

11. Use of cannabidiol oil by caregivers: a focus on Alzheimer's disease Magdalena Leszko

12. Medicinal use of cannabis: adverse events as a balanced perspective Giada Crescioli, Valentina Maggini, Fabio Firenzuoli, Alfredo Vannacci and Niccolo Lombardi

II. Physiological aspects and metabolic aspects

13. Physiopathology and use of cannabinoids for fibrotic diseases Carmen del Rio and E. Munoz

14. Cannabinoids in inflammation and atherosclerosis Leonor Thomson, Edward Moreira-Bahnson and Bruno Musetti

15. Targeting the CB(2) receptors and other endocannabinoid elements to delay disease progression in cardiovascular diseases Shreesh Ojha

16. BMI in cannabis users: regulation, mechanisms and public health impact Thomas Clark

III. Neurological, psychological and behavioural aspects

17. Neuroprotection by cannabis related products, cannabidiol and cannabigerol, and associated mechanisms of action Carolina Echeverry Sr., Jimena Fagetti, Miguel Reyes-Parada and Cecilia Scorza

18. Cannabis terpenes as neuroprotective agents: a focus on alpha-bisabolol John Staton Laws, Srijan Shrestha and Scott D. Smid

19. Cannabidiol in medicinal usage of stress: modelling investigations into cocaine M. Julia García-Fuster and Olga Valverde

20. Medicinal cannabis and neurocognition impairment Caroline MacCallum, April Christiansen, Lindsay Lo, Carly Pistawka, Michael Boivin and Melissa Snider-Adler

21. Genetic models of audiogenic seizures: what they are and how cannabinoids and Cannabis-derived compounds can be used to alleviate their symptoms - an updated narrative Norberto Garcia-Cairasco

22. Addressing the validity of cannabinoid therapy as an option for the treatment of substance use disorder Rose Chesworth, Erin McLemon and Tim Karl

IV. Pharmacological and cellular aspects

23. Cannabidiolic acid (CBDA), features and profiles: anti-hyperalgesic effects G. Singh, Katja Linher-Melville and Raphael Mechoulam

24. Cannabis-drug interactions: implications for medicinal cannabis use Fran Gengo, Anna Mattle and Christopher Ralyea

25. Cannabinoid receptor subtype 2 (CB2R): features and targets for medical applications Marialessandra Contino, Carmen Abate, Nicola Antonio Colabufo, Francesco Leonetti and Angela Stefanachi

26. Medical use of cannabidiol and impact on cancer cell viability Kent E. Chair and Wesley Raup-Konsavage

27. Anti-inflammatory and antioxidant and immunomodulatory effects of phytocannabinoid ß-caryophyllene: A mechanistic overview Vafa Baradaran Rahimi, Arghavan Memarzia and Prof. Vahid Reza Askari

V. Symptom Control and Medicinal Uses

28. Cancer patients and providers: Attitudes and beliefs of cannabis and cannabinoids use as a treatment Kimberson Tanco

29. CBD (cannabidiol) use in breast cancer chemotherapy Ana I. Torres-Suarez, Ana Isabel Fraguas-Sánchez and Ana Fernández-Carballido

30. Sleep: cannabis and cannabinoids use Eric Murillo-Rodríguez

31. Cannabis and cannabis related products and their uses in aiding sexual health of men and women Lynnette Nathalie Lyzwinski

32. Symptom control in palliative care settings: The role of cannabis-based medicines Maximillian Stevenson and Leah Sera

33. Cannabidiol (CBD) Use in Fragile X Spectrum Disorders Devon Johnson and Randi J. Hagerman

34. Hempseed (Cannabis sativa) and ameliorative effects in hypercholesterolemia NAVEEN KAUSHAL

35. Benzodiazepines and cannabis use Chad Alexander Purcell

36. Features of (+)-trans-cannabidiol-2-hydroxy pentyland applications to disease: a focus on usage in diabetic nephropathy E. Munoz, Matthias Winkler, Marcus Goetz and Isabel Gonzalez Mariscal

37. Medical use of cannabis: applications to Tourette syndrome Kirsten R. Müller-Vahl and Natalia Szejko

38. Cannabinoids and their use in chronic non-cancer pain: a new narrative review Stanley Sau-Ching Wong and Chi Wai Cheung

39. Endometriosis: features and potential role of medical cannabis Mike Armour and Justin Sinclair

40. Cannabis usage for Crohn's disease and ulcerative colitis: a narrative Joseph Feuerstein and Rajsavi Anand

41. Medical cannabis and use in migraine Jessica Jiang and Alasdair M. Barr

42. Cannabidiol (CBD ) and potential in medicinal use in rheumatoid arthritis Torsten Lowin

43. Role of Cannabinoids in Glaucoma: Lowering Intraocular Pressure or Neuroprotection Ujendra Kumar, Sneha Singh and Rishi Somvanshi

44. Medicinal potential of anandamide as a representative endocannabinoid and its effect at the cellular level in skin Adrianna Maria Piasek and Anna Sobiepanek

VI. Resources

45. Medical Cannabis and Resources Rajkumar Rajendram