Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases

Contains contributions from the best scientists in medicinal chemistry who present the latest developments in the field

Kelly Chibale (Volume editor)

9780128198667, Elsevier Science

Hardback, published 25 October 2019

232 pages
22.9 x 15.1 x 2.1 cm, 0.5 kg

Medicinal Chemistry Approaches to Malaria and Other Tropical Disease, Volume 53 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

1. A decade of malaria phenotypic screenings: Key lessons on the discovery and development of new antimalarial drugs Esther Fernández, María Isabel Castellote, María Jesús Chaparro, Beatriz Díaz, Jorge Fernández, Mariola Gordo, Laura de las Heras, María Luisa León, Lourdes Rueda and Félix Calderón 2. Medicinal chemistry progression of antimalarial hits from phenotypic whole cell screening of SoftFocus libraries Peter M. Cheuka, Godfrey Mayoka, John Okombo and Kelly Chibale 3. The hybrid antimalarial approach Princy Gupta, Lovepreet Singh and Kamaljit Singh 4. Dealing with schistosomiasis: Current drug discovery strategies Sandra Gemma, Stefano Federico, Simone Brogi, Margherita Brindisi, Stefania Butini and Giuseppe Campiani 5. Shortcuts to schistosomiasis drug discovery: The state-of-the-art José T. Moreira-Filho, Rafael F. Dantas, Mário R. Senger, Arthur C. Silva, Dulcinea M. B. Campos, Eugene Muratov, Floriano P. Silva-Junior, Carolina H. Andrade and Bruno J. Neves 6. Multicomponent reactions: A mighty journey partner for infectious tropical disease drug discovery Diego Muñoz-Torrero, Rodolfo Lavilla, F. Javier Pérez-Areales and Ouldouz Ghashghaei

Subject Areas: Organic chemistry [PNN], Pharmacology [MMG]