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Medical Toxicology of Occupational and Environmental Exposures, Volume 3
Carcinogens: Risk Factors, Pathophysiology, Susceptibility, and Clinical Abnormalities

Donald G. Barceloux (Author), Robert B. Palmer (Edited by)

9781119881261, Wiley

Hardback, published 11 June 2026

752 pages
27.4 x 22.1 x 4.8 cm, 1.905 kg

Medical Toxicology of Occupational and Environmental Exposures is the only reference which comprehensively covers the clinical, analytical, and monitoring information needed by clinicians, students and investigators with interests in metals, radiation, and cancer. The information in all chapters is presented in a cogent, standardized format which greatly simplifies the use of the text as a reference. Reviewed by a distinguished panel of well-known toxicology experts, the information is critically evaluated and authoritative. The interdisciplinary, evidence-based approach is designed to reach beyond clinical settings to increase the scientific understanding of those in associated fields (analytical laboratories, universities, federal and state regulatory and environmental agencies) involved with decisions regarding metals, radiation, and chemical carcinogens. The consistent and concise style allows the reader to quickly locate the appropriate information necessary for informed decisions regarding the sources, host susceptibility, dose-response, clinical effect, health surveillance, and management of exposures to these substances.  Additional information is readily available to the interested reader through the detailed bibliography at the end of each chapter.

  • Volume 3 "Carcinogens, Risk Factors, Pathophysiology, Susceptibility, and Clinical Abnormalities" provides concise, comprehensive coverage of the genetic background and an organ-based approach to cancer-causing exposures, histology, host susceptibility, and clinical features.

Foreword xxi

Preface xxiii

Acknowledgments xxv

Review Panel xxvi

Volume 3 Carcinogens: Risk Factors, Pathophysiology, Susceptibility, and Clinical Abnormalities 1

A Carcinogenesis 3

47 Carcinogenesis 5

B Chemical Carcinogenicity 57

48 General Principles 59

49 Evaluating Carcinogenicity 75

50 Carcinogen Classifications 151

51 Risk Assessment 169

52 Cancer Surveillance 203

C Tumor Sites 217

53 Respiratory Tract 219

54 Gastrointestinal Tract 273

55 Urinary Tract 337

56 Male Reproductive Tract 365

57 Female Reproductive Tract 391

58 Central Nervous System 441

59 Leukemia 483

60 Lymphomas 539

61 Skin 629

62 Soft Tissue and Bone Sarcomas 667

63 Thyroid 691

Index 705

Subject Areas: Chemistry [PN]

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