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Mechanotransduction

This special volume of Progress in Molecular Biology and Translational Science focuses on mechanotransduction.

Adam J. Engler (Volume editor), Sanjay Kumar (Volume editor)

9780123946249

Hardback, published 30 July 2014

384 pages
22.9 x 15.1 x 2.6 cm, 0.84 kg

Praise for the series: "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal

Approx.370 pages

Subcellular tools for activating and measuring mechanotransductive signaling

1. The Detection and Role of Molecular Tension in Focal Adhesion Dynamics Brenton D. Hoffman 2. Single Cell Imaging of Mechanotransduction in Endothelial Cells Shaoying Lu and Yingxiao Wang

Focal adhesions as sensors

3. Focal Adhesions as Sensors Jean-Cheng Kuo 4. Focal Adhesions as Sensors Wolfgang H. Goldmann 5. Mechanical Cues Direct Focal Adhesion Dynamics Kristina Haase, Zeinab Al-Rekabi and Andrew E. Pelling 6. Molecular Mechanisms Underlying the Force-Dependent Regulation of Actin-to-ECM Linkage at the Focal Adhesions Hiroaki Hirata, Masahiro Sokabe and Chwee Teck Lim

Nuclear Mechanisms of Sensing

7. The Cellular Mastermind(?) – Mechanotransduction and the Nucleus Ashley Kaminski, Gregory R. Fedorchak and Jan Lammerding 8. Nuclear Forces and Cell Mechano-Sensing Samer Alam, David B. Lovett, Richard B. Dickinson, Kyle J. Roux and Tanmay P. Lele

Mechano-sensing in Stem Cells

9. From Stem Cells to Cardiomyocytes: The Role of Forces in Cardiac Maturation, Aging, and Disease Gaurav Kaushik and Adam J. Engler 10. Matrix Regulation of Tumor-Initiating Cells Sophie Y. Wong and Sanjay Kumar 11. Biomaterials Approaches in Stem Cell Mechanobiology Nikolche Gjorevski and Matthias Lutolf

Multi-cellular Sensing

12. Mechanotransduction in C. elegans Morphogenesis and Tissue Function Erin J. Cram 13. Mechanical Force Sensing in Tissues Soline Chanet and Adam C. Martin

Subject Areas: Cellular biology [cytology PSF], Molecular biology [PSD]

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