Mechanisms of Memory

A graduate text reference, this book provides a unique overview of the cellular and molecular mechanisms involved in learning and memory.

J. David Sweatt (Edited by), J. David Sweatt (Author)

9780123749512, Elsevier Science

Hardback, published 12 November 2009

362 pages
27.6 x 21.5 x 2.5 cm, 1.44 kg

This fully revised second edition provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader’s understanding.

1. Introduction - the basics of psychological learning and memory theory2. Studies of human learning and memory3. Non-associative learning and memory4. Rodent behavioral learning and memory models5. Associative learning and unlearning6. Hippocampal Function in Cognition7. Long-term Potentiation: A Candidate Cellular Mechanism for Information Storage in the CNS8. The NMDA Receptor9. Biochemical mechanisms for information storage at the cellular level10. Molecular genetic mechanisms for long-term information storage at the cellular level11. Inherited disorders of human memory – mental retardation syndromes12. Aging-related memory disorders – Alzheimer’s DiseaseAPPENDIX. The Basics of Experimental Design

Subject Areas: Molecular biology [PSD], Neurosciences [PSAN], Genetics [non-medical PSAK], Neurology & clinical neurophysiology [MJN], Cognition & cognitive psychology [JMR]