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Mechanisms of Drug Action on the Nervous System

R. W. Ryall (Author)

9780521274371, Cambridge University Press

Paperback, published 25 May 1989

256 pages
21.6 x 13.8 x 1.4 cm, 0.342 kg

'Most students will find it an excellent aid to their lecture course … This first text deserves to be recommended to a wide range of students.' Trends in Pharmacological Sciences

Drugs affecting the nerves and the brain are among the most commonly used in contemporary medicine. This book examines the mechanism by which such substances cause their therapeutic effects or undesirable side-effects, in relation to underlying physiological and pathological processes. This new edition has been extensively revised and reorganised; the section on the autonomic system has been greatly expanded. Other changes reflect the significant advances in our understanding of drug action in the peripheral and central nervous systems which have arisen through the application of new electrophysiological and computer techniques. The volume summarises the explosion of information concerning endogenous opioids, other peptides, the benzodiazepines and their receptors. Later chapters deal with the activity and role of drugs in a number of disorders including epilepsy, schizophrenia and depression. This textbook is suitable for undergraduates in pre-clinical medical sciences, pharmaceutical and natural sciences; and for post-graduates and trainees in neuroscience, psychiatry and anaesthesia.

Preface to the second edition
Preface to the first edition
List of abbreviations
1. Introduction
2. Techniques
Part I. Peripheral Nervous System: 3. Neuromuscular junction
4. Autonomic nervous system
Part II. Central Nervous System: 5. Central neurotransmitters and neuromodulators
6. The blood-brain barrier
7. General anaesthetics
8. Pain and analgesia
9. Drug interactions with inhibitory amino acids
10. Drugs used in schizophrenia
11. Affective and manic depression
12. Disorders associated with defined brain lesions
Selected reading
Index.

Subject Areas: Neurology & clinical neurophysiology [MJN]

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