Mechanics of Biomaterials
Fundamental Principles for Implant Design

Combining materials science, mechanics, implant design and clinical applications, this self-contained text provides a complete grounding to the field.

Lisa A. Pruitt (Author), Ayyana M. Chakravartula (Author)

9780521762212, Cambridge University Press

Hardback, published 20 October 2011

698 pages, 375 b/w illus. 35 tables 115 exercises
25.4 x 20.3 x 3.8 cm, 1.62 kg

'Mechanics of Biomaterials: Fundamental Principles for Implant Design provides a much needed comprehensive resource for engineers, physicians, and implant designers at every level of training and practice. The book includes a historical background which outlines the engineering basis of traditional implant designs, and interactions of materials, biology, and mechanics resulting in clinical success or failure of these devices. Each chapter contains a detailed description of the engineering principles which are critical to understand the mechanical behavior of biomaterials and implants in vivo. The scope of the text covers orthopaedics, cardiovascular devices, dental, and soft tissue implants, and should help considerably in our efforts to improve the function and durability of biomaterials and implants used in clinical practice.' Michael Ries, University of California, San Francisco

Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field. Split into three sections: Materials, Mechanics and Case Studies, it begins with a review of sterilization, biocompatibility and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues and presents case studies in four key clinical areas: orthopedics, cardiovascular devices, dentistry and soft tissue implants. Each chapter ends with a list of topical questions, making this an ideal course textbook for senior undergraduate and graduate students, and also a self-study tool for engineers, scientists and clinicians.

Part I. Materials: 1. Biocompatibility, sterilization and materials selection for implant design
2. Metals for medical implants
3. Ceramics
4. Polymers
5. Mechanical behavior of structural tissues
Part II. Mechanics: 6. Elasticity
7. Viscoelasticity
8. Failure theories
9. Fracture mechanics
10. Fatigue
11. Friction, lubrication and wear
Part III. Case Studies: 12. Regulatory affairs and testing
13. Orthopedics
14. Cardiovascular devices
15. Oral and maxillofacial devices
16. Soft tissue replacements
Appendix A. Selected topics from mechanics of materials
Appendix B. Table of material properties of engineering biomaterials and tissues
Appendix C. Teaching methodologies in biomaterials
Glossary
List of symbols.

Subject Areas: Molecular biology [PSD], Biomedical engineering [MQW], Biomechanics, human kinetics [MFGV]