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Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease

A cutting edge review of lung epithelial regulation, focusing on intercellular interactions and how these processes are impaired in human disease

Venkataramana K Sidhaye (Author), Michael Koval (Author)

9780128038093

Hardback, published 16 March 2017

276 pages
27.6 x 21.5 x 2.2 cm, 1.04 kg

"...a very comprehensive book that deals with the lung epithelial biology and molecular signaling involved in the normal lung and their implications in disease pathogenesis. It is very well written by experts in the field, highly illustrated, and presented in a very readable format. It is highly recommended for any clinician or scientist who is interested in the molecular and cellular workings of the lung. Score: 92 - 4 Stars" --Doody's

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters.

Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition.

1. Junctional Interplay in Lung Epithelial Barrier Function2. Ion Transport and Lung Fluid Balance3. Glucose Transport and Homeostasis in Lung Epithelia4. Pulmonary Surfactant Trafficking and Homeostasis5. Integrin Regulation of the Lung Epithelium6. Epithelial Regeneration and Lung Stem Cells7. The Function of Epithelial Cells in Pulmonary Fibrosis8. The Role of Epithelial Cell Quality Control in Health and Disease of the Distal Lung9. The Respiratory Epithelium in COPD10. Acute Respiratory Distress Syndrome11. Epithelial Barrier Dysfunction in Asthma12. Cystic Fibrosis: An Overview of the Past, Present, and the Future

Subject Areas: Cardiothoracic surgery [MNH], Clinical & internal medicine [MJ]

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