Leucocyte Adhesion

Klaus Ley (Edited by)

9780123749093, Elsevier Science

Hardback, published 24 November 2009

300 pages
22.9 x 15.1 x 2.3 cm, 0.68 kg

Leucocyte Adhesion provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. This volume provides a review of the latest developments in leukocyte adhesion. Regulation of cell adhesion is important for immune system function.

1. Membrane composition and properties
Lipid rafts (open)
Membrane tethers
(R Waugh, Rochester)
Microvilli
(JY Shao, Wash U)
Whole cell deformation
(D Khismatullin, Tulane)

2. Adhesion molecules
Integrin activation
(M. Shimaoka, Harvard)
Cytoskeletal anchoring
(Fred Pavalko, Iowa)
No tile yet
(Alon, Weizman)
Catch bonds
(Cheng Zhu, Georgia Tech and Roger McEver, OMRF)
Modeling adhesion
(Pospieszalska/Ley, LIAI)
Factors limiting the onset of bond formation at cell interfaces
(R Waugh, Rochester)

3. Active role of endothelial cells
Adhesive platforms
(O. Barreiro, Madrid)
Migratory cups, podosomes
(Chris Carman, Beth Israel)
PECAM recycling
(WA Muller, Northwestern)

4. Methods
1. FRET
(Minsoo Kim, Rochester)
2. Flow chambers
(Simon SI at UC Davis)

Subject Areas: Cellular biology [cytology PSF], Biochemistry [PSB]