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Lactic Acid Bacteria as Cell Factories
Synthetic Biology and Metabolic Engineering

Focuses on synthetic biology and metabolic engineering contributions towards optimizing production of biomolecules, bioactive health-promoting compounds by LAB and other properties

Didier Montet (Edited by), Ramesh C. Ray (Edited by), Vasco Ariston De Carvalho Azevedo (Edited by), Spiros Paramithiotis (Edited by)

9780323919302, Elsevier Science

Paperback / softback, published 15 May 2023

438 pages, 130 illustrations (40 in full color)
22.9 x 15.2 x 2.8 cm, 0.45 kg

Lactic Acid Bacteria as Cell Factories: Synthetic Biology and Metabolic Engineering describes the most recent developments on the metabolic engineering and synthetic biology of Lactic Acid Bacteria (LAB) for production of biologically active biomolecules (enzymes, organic acids, bacteriocins, bioactive peptides, etc.), recombinant proteins, and their role in bioremediation. The book focuses on synthetic biology and metabolic engineering for the production of biologically active molecules such as bioactive peptides, polysaccharides, vitamins (Riboflavin), enzymes, organic acids (lactic and gamma-aminobutyric acid), flavor and aroma compounds, bacteriocins, recombinant proteins, etc.

Individual chapters are devoted to the production of biosurfactants and their applications and the bioremediation of heavy metals by LAB from aquatic environments. Two critical chapters address Genome editing of LAB: opportunities for food, feed and pharmaceuticals and A synthetic biology approach for plasmid DNA and Recombinant protein production. This book will be a valuable resource for those working in biology, biotechnology, biological engineering, chemical engineering, microbiology, food science and technology, genetics and synthetic biology.

1. LAB as cell factories: A synthetic biology approach for plasmid DNA and recombinant protein production

Fernanda Alvarenga Lima Barroso, Lu´s Claudio Lima de Jesus, Tales Fernando da Silva, Andria dos Santos Freitas, Monique Ferrary Americo, Lucas Jorge da Silva Fernandes, < Rafael de Assis Gloria, Gabriela Munis Campos, Rodrigo Dias de Oliveira Carvalho, Tu´lio Marcos Santos, Juliana Guimaraes Laguna, and Vasco Ariston de Carvalho Azevedo

2. Synthetic biology and metabolic engineering for improvement of lactic acid bacteria as cell factories

Mohammad Towsif Hossain

3. Overview of traditional, emerging, and future applications of LAB and most important contributions of genome editing tools for food, feed, and pharmaceuticals

Elsaadani Moez, Tarek Sahar, Wafaa Donia, and Didier Montet

4. Lactic acid bacteria in biorefineries

Katarzyna Polanowska

5. Lactic acid microbial production and recovery: Review and recent advances in bioprocess integration

Catherine Beal, Pedro Arana-Agudelo, Tahmineh Farel, < Marwen Moussa, and Violaine Athe`s

6. Lactic acid bacteria for riboflavin production

Spiros Paramithiotis and Chrysanthi Pateraki

7.  Lactic acid bacterial cell factories for the production of gamma-aminobutyric acid

Spiros Paramithiotis and Chrysanthi Pateraki

8.  Use of exopolysaccharides from lactic acid bacteria to develop cereal-based food: Perspectives and challenges for Burkina Faso

Fidele Wend-Ben< edo Tapsoba, Larissa Yacine Ware, < Serge Samandoulougou, Diarra CompaoreS

14.  Lactic acid bacteria as biocontrol agents of food pathogens

Omotola Folake Olagunju and Oluwatosin Ademola Ijabadeniyi

15. Biotechnology of bacteriocins production by LAB

Justine Ma?wore and Jean-Justin Essia Ngang

16. Synthetic biology approaches for biosurfactants production by lactic acid bacteria

Joana L. Rodrigues and Ligia R. Rodrigues

17. Biosurfactants production by LAB and emerging applications

Vasiliki Kachrimanidou, Maria Alexandri, Dimitra Alimpoumpa, Iliada K. Lappa, Aikaterini Papadaki, and Nikolaos Kopsahelis

18.  The reducing power of LAB in fermentation and biomass production Remy Cachon

19. Bioremediation of heavy metals from aquatic environments by lactic acid bacteria

Arumugam Sundaramanickam, Surabhi Awasthi, and Vishwas Patel

20.  Lactic acid bacteria and Bifidobacterium as potential psychotherapeutics

Gargi Dey

Subject Areas: Fitness & diet [VFM], Food & beverage technology [TDCT], Biotechnology [TCB]

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