Keynes & Aidley's Nerve and Muscle

A complete, yet accessible and up-to-date, introduction to the cellular physiology of nerve, and skeletal, cardiac and smooth muscle.

Christopher L.-H. Huang (Author)

9781108495059, Cambridge University Press

Hardback, published 19 November 2020

324 pages, 24 b/w illus.
25.2 x 19.2 x 2.1 cm, 0.93 kg

'Professor Christopher Huang has updated and significantly broadened the scope and the translational endpoints of the classical textbook of Integrative and Cell Physiology Keynes & Aidley's Nerve and Muscle. The result is a comprehensive, well planned, logically presented and extensively referenced monograph. Based on the text and supporting figures, it builds on the strengths of the parent textbook while also providing new in-depth coverage of recent advances in neurophysiology as well as skeletal and cardiac muscle electrophysiology and contractility. The internationally recognized research accomplishments of Professor Huang on key cell physiology mechanisms of the heart and skeletal muscle form the basis of very informative material concerning cardiac rhythm disturbances and some aspects of exercise physiology and aging. This textbook will serve as a valuable resource for undergraduates, graduate students, as well as both basic science and clinical faculty members in Life Sciences.' Wayne Giles, University of Calgary, Canada

This well-established and acclaimed textbook introducing the rapidly growing field of nerve and muscle function has been completely revised and updated. Written with undergraduate students in mind, it begins with the fundamental principles demonstrated by the pioneering electrophysiological experiments on cell excitability. This leads to more challenging material recounting recent discoveries from applying modern biochemical, genetic, physiological and biophysical, experimental and mathematical analysis. The resulting interdisciplinary approach conveys a unified contemporary understanding of nerve and skeletal, cardiac and smooth muscle function at the molecular, cellular and systems levels. Emphasis on important strategic experiments throughout clarifies the basis for our current scientific views, highlights the excitement and challenge of biomedical discovery, and suggests directions for future advances. These fundamental ideas are then translated into discussions of related disease conditions and their clinical management. Now including colour illustrations, it is an invaluable text for students of physiology, neuroscience, cell biology and biophysics.

Preface
Acknowledgements
List of abbreviations
1. Structural organization of the nervous system
2. Resting and action potentials
3. Background ionic homeostasis of excitable cells
4. Membrane permeability changes during excitation
5. Voltage-gated ion channels
6. Cable theory and saltatory conduction
7. Neuromuscular transmission
8. Synaptic transmission in the nervous system
9. The mechanism of contraction in skeletal muscle
10. The activation of skeletal muscle
11. Excitation-contraction coupling in skeletal muscle
12. Contractile function in skeletal muscle
13. Cardiac muscle
14. Ion channel function and cardiac arrhythmogenesis
15. Smooth muscle
Further reading
References
Index.

Subject Areas: Neurosciences [PSAN], Biophysics [PHVN], Neurology & clinical neurophysiology [MJN], Physiology [MFG], Physiological & neuro-psychology, biopsychology [JMM]