Ketamine for Treatment-Resistant Depression
Neurobiology and Applications

Simple and evidence-based overview of the neurobiology and usage of ketamine as a therapeutic for treatment-refractory depression

Gustavo H. Vazquez (Edited by), Carlos A. Zarate (Edited by), Elisa Brietzke (Edited by)

9780128210338, Elsevier Science

Paperback, published 18 September 2020

168 pages
23.4 x 19 x 1.2 cm, 0.36 kg

"This is the first book that specifically focuses on ketamine for treatment-resistant depression. This topic has been covered in lectures, articles, and briefly in some textbooks, but this is the first book I have read that specifically covers it. Given the limited available data, the book succeeds in its stated goal to inform readers about what is currently known about ketamine. Updated editions will be needed to reflect the growing knowledge base and eventual treatment strategies using ketamine." --© Doody’s Review Service, 2020, Aaron Plattner, MD(Pine Rest Christian Mental Health Services), reviewer, expert opinion

Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics.

1. Ketamine, Clio, and the hippocratic triangled fragments of the history of ketamine
2. Ketamine’s potential mechanism of action for rapid antidepressive effects – a focus on neuroplasticity
3. Treatment resistant depression
4. Suicide in psychiatric disorders: rates, risk factors, and therapeutics
5. Overview of ketamine for major depression: efficacy and effectiveness
6. How to implement a ketamine clinic
7. Development of new rapid-action treatments in mood disorders
8. Closing remarks

Subject Areas: Neurosciences [PSAN]