Isolated Pyranones
Multifaceted Building Blocks for Molecular Diversity

Covers the latest findings on synthesis and chemical reactivity of highly functionalized pyran-2-ones and pyran-4-ones and their applications in drug discovery and material sciences

Vishnu Ji Ram (Author), Atul Goel (Author), Ramendra Pratap (Author)

9780128212165

Paperback, published 3 May 2022

276 pages, 100 illustrations
22.9 x 15.1 x 1.8 cm, 0.45 kg

Isolated Pyranones: Multifaceted Building Blocks for Molecular Diversity covers the latest findings on synthesis and chemical reactivity of highly functionalized pyran-2-ones and pyran-4-ones, their reduced analogs and compounds derived from them through chemical reactions, and their applications in drug discovery and material sciences. It covers the mechanisms of the reaction and step by step formation of final products. Numerous pyranones from natural and synthetic origins, as well as their derived products, have shown diverse pharmacological activities and some are in clinical use. The applications of these compounds are not limited to drug development and imaging agents, and they are also used in material science as organic semiconductors, liquid crystals, organic light emitting diodes (OLEDs), organic catalysts, solid state lasers, photovoltaic and photoconductive devices. The book is ideal for organic, bioorganic, physical, material and natural product chemists working to generate diverse molecular entities through ring transformation reactions of pyranones, and those working in material science to generate new chemical entities.

1. Introduction2. Characteristics of pyranones3. Chemistry of isolated 2- pyranones4. Chemistry of 2H-pyran-3(4H)-one5. Chemistry of isolated 4-pyranones6. Medicinal significance of natural and synthetic pyranones7. Application of pyranones in material science9. Conclusion

Subject Areas: Organic chemistry [PNN]