iPSCs - State of the Science

A timely, important collection of new information and applications that addresses research on how iPSCs can be derived from different sources

Alexander Birbrair (Edited by)

9780323857673, Elsevier Science

Paperback / softback, published 19 January 2022

316 pages, 60 illustrations (40 in full color)
23.5 x 19 x 2.1 cm, 0.66 kg

iPSCs - State of the Science, Volume Sixteen, the latest release in the Advances in Stem Cell Biology series, is an expansive collection of information and new discoveries in the field. This volume addresses the importance of induced pluripotent stems cells and how can they be derived from different sources. It addresses advances in research in induced pluripotent stem cells from alternate sources, such as spermatogonial stem cells, ovarian tissue, cancer cells, and many other sources. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors.

1. Revealing Nervous and Cardiac System Interactions by iPSC-Based Platforms 2. Human iPSC Models of Cardiac Electrophysiology and Arrhythmia 3. Human iPSCs for Modeling of Hepatobiliary Development and Drug Discovery 4. The application of iPSC-derived kidney organoids and genome editing in kidney disease modeling 5. Towards the in vitro understanding of iPSC nucleoskeletal and cytoskeletal biology, and their relevance for organoid development 6. Induced Pluripotent Stem Cell Models for Mitochondrial Disorders 7. Induced Pluripotent Stem cells for Studying Genetic Autonomic Disorders 8. Applications of iPSCs in Gaucher Disease and other rare sphingolipidoses 9. Application of CRISPR/Cas system in iPSC-based disease model of hereditary deafness 10. Progress and Possibilities for Patient-Derived iPSCs and Genetically Engineered Stem Cells in Cancer Modeling and Targeted Therapies

Subject Areas: Life sciences: general issues [PSA]